Viszeral- und
Thoraxchirurgie

Portrait Prof. Dr. med. Stefan Breitenstein

Prof. Dr. med. Stefan Breitenstein

Direktor Departement Chirurgie
Leiter Darm- und Pankreastumorzentrum
Chefarzt, Leiter Viszeralchirurgie
Klinik für Viszeral- und Thoraxchirurgie
Facharzt für Chirurgie

Current Position
Chairman Department of Surgery and Chief of Visceral and Thoracic Surgery

Professional Experience
1995–1996Resident, Department of Surgery, Cantonal Hospital Uznach, Switzerland (Dr. R. Rüegger, MD)
1996–1998Resident, Department of Surgery, Regional Hospital Wetzikon Switzerland (Dr. H. Wehrli, MD)
1998–2000Chief Resident, Department of Surgery, Kantonsspital Winterthur Switzerland (Prof. M. Decurtins, MD)
2000–2001Attending Surgeon, Traumatology, Department of Surgery, Kantonsspital Winterthur, Switzerland (Prof. M. Decurtins, MD)
2001–2002Attending Surgeon, Visceral and Thoracic Surgery, Department of Surgery, Kantonsspital Winterthur, Switzerland (Prof . M. Decurtins, MD)
2002–2004Senior Surgeon, Team-Leader Visceral- und Thoracic Surgery, Department of Surgery, Kantonsspital Winterthur, Switzerland (Prof. M. Decurtins, MD)
2004–2006Senior Surgeon, Department of Visceral and Transplantation Surgery University Hospital, Zurich, Switzerland (Prof. P.-A. Clavien, MD, PhD)
2006–2012Team-Leader HPB-Surgery, Senior Surgeon, Department of Visceral and Transplantation Surgery, University Hospital, Zurich, Switzerland (Prof. P.-A. Clavien, MD, PhD)
2008–2012Member of the Board of Directors of the Swiss HPB Center
2009–2012Consultant Surgeon, Department of Visceral and Transplantation Surgery, University Hospital, Zurich, Switzerland (Prof. P.-A. Clavien, MD, PhD)
seit 2012Chairman Department of Surgery and Chief of Visceral and Thoracic Surgery, Kantonsspital Winterthur
Educational Degrees
1994Medical Approbation University of Zurich, Switzerland
1999Medical Doctor: “Langzeitresultate nach Ersatz der Aorta thoracica descendens sowie der Aorta thoracoabdominalis“, University Hospital Zurich
2002Board of Surgery (FMH specialist in surgery)
2005Visceral Surgery Specialist, (Schwerpunkttitel für Viszeralchirurgie)
2006General Surgery and Traumatology Specialist, (Schwerpunkttitel für Allgemein- und Unfallchirurgie)
2007Clinical Assistant Professor, Department of Viszeral and Transplantation Surgery, University Hospital Zurich
2009European Board of Surgery, Section HPB, EBSQ
2010Venia legendi (Privatdozent) Visceral und Transplant Surgery, University Zurich

Memberships

  • Board Member, Swiss Society of Surgery (SGC)
  • Senior Editor–Swiss Knife (SGC Journal)
  • Treasurer – Swiss Society of Clinical Nutrition (GESKES)
  • Board member Local Educational and Clinical Practice Committee – The European Society of Clinical Nutrition and Metabolism (ESPEN)
  • Swiss Association for Laparoscopic and Thoracoscopic Surgery (SALTC)
  • Swiss Society of General Surgery and Traumatology (SGAUC) vSwiss Association of Visceral Surgery (SGVC) vSwiss Study Group for Colo-Proctology
  • Research Section of the Swiss Surgical Society (RS-SSS)
  • Minimally Invasive Robotic Association (MIRA)
  • European HBP Association (EHPBA)
  • Member of the Swiss Tumor Board for Colorectal Cancer

Awards

  • Poster-Prize, SGC Congress 2000, Meier C. Wildermuth S. Breitenstein S. Marincek B. “Virtuelle MR Kolonoskopie als präoperative Abklärung bei kolorektalen Karzinomen“
  • Video-Prize, SGC Congress 2003, Goti F. Breitenstein S. Wille G. Gianom D. Decurtins M. „Lokalanästhesie bei Leistenhernieneingriffen–Vorgehen und Tricks aus der klinischen Anwendung“
  • PIZ (Patient im Zentrum) Prize 2005, University Hospital Zurich, Breitenstein S, Müller S, Schiesser M, Schäfer M, „Mangelernährung und Ernährungstherapie in der Chirurgie“
  • Poster-Prize, SGC Congress 2006, Breitenstein S. Kraus A. Hahnloser D. Demartines N. Clavien P „Emergency Left Colon Resection for Acute Perforation. Primary Anastomosis or Hartmann’s Procedure? A Case-Matched Control Study”
  • Award for Innovation 2006, Department of Visceral and Transplantation Surgery, USZ for the “Weekly Surgical and Gastroenterological Grand Rounds and the Teleconference”
  • Forschungs-Förderungspreis 2008 by Schweiz. Gesellschaften für Gastroenterologie und Viszeralchirurgie for “Robotic Assisted vs. Laparoscopic Cholecystectomy, Outcome and cost analysis in a Case-Matched Control Study”
  • Award for Clinical Research, academic achievements 2008 Department of Visceral and Transplantation Surgery, USZ
  • Senior Hepatology Prize 2010 for “Quality, Safety and Protection in Liver Surgery” by Schweizerische Gesellschaften für Gastroenterologie und Schweizerische Gesellschaft für Viszeralchriurgie, Sept 2010
  • Swiss Transplant Research Award 2011, 3. Prize, for “Effects of Pentoxifylline on Liver Regeneration: A Double-Blinded, Randomized, Controlled Trial in 101 Patients Undergoing Major Liver Resection”(first authorship shared: S. Petrowsky, S. Breitenstein, K. Slancamenac)
  • Surgery Award 2011, Perforated left colonic diverticulitis with purulent or fecal peritonitis: Primary Anastomosis or Hartmann’s Procedure? – A Multicenter Randomized Controlled Trial
  • Swiss Society of Gastroenterology and Visceral Surgery, Lausanne, Sept 29-30, 2011
  • Surgery Prize 2012, Protection of pharmacological Postconditioning

Grants

  • 2005/2006: „Prospektiv randomisierte Studie Hartmann versus primäre Anastomose mit protektiver Ileostomie bei Kolonperforation“,CHF 20’000, from Nycomed
  • 2006: „Effect of preoperative oral supplementation with immune-modulating nutrients in well nourished patients undergoing major abdominal surgery – Prospective randomized trial“, CHF 10’000, from Fresenius
  • 2009: Travel Grant, 7’000 CHF, from Nycomed
  • 2009: Swiss HPB Center, Screen project, 30’000 CHF, from Bayer
  • 2011: Research Grant for Enoscopic Surgery , Covidien Fellowship: 50’000CHF
  • 2011: SNF Grant, Primary Investigator, for „Konditionierung mit volatilen Anästhetika in der Lebertransplantation“, 331’000 CHF
  • 2011: SNF Grant (Co Investigator), Institutional Partnership in HPB Surgery: Tashkent (Uzbekistan) and Zurich (Switzerland): 134’000CHF
  • 2011: Matching Grant of Zentrum für Klinische Forschung (ZKF) of the University Hospital Zurich
  • for the project ”Randomized controlled trial comparing single port versus four port cholecystectomy”, 75’000 CHF
  • 2011: Matching Grant of Zentrum für Klinische Forschung (ZKF) of the University Hospital Zurich for the project ” Downstaging of unresectable intrahepatic or hilar cholangiocellular carcinoma by selective intra-arterial floxuridine and systemic cisplatin and gemcitabine A dose finding single center phase I study Samaras P. and Breitenstein S. (Co Primary Investigators): 75’000 CHF

Teaching and Training Functions

  • Tutor and assistant professor (Privatdozent) University of Zurich Medical School (2000–today)
  • Mentorship of Master’s and Doctoral Students
  • Master Thesis: Which biochemical markers should be used for detection and post treatment follow-up of neuroendocrine liver metastases? A systematic review protocol Stephan Arigoni, Matriculation No: 08-214-967, University of Zurich, Switzerland
  • Master Thesis: Should genetic signatures be used in the prediction of neuroendocrine liver metastases and to inform treatment decisions? A systematic review protocol Jonas Betschart, Matriculation No: 08-740-367, University of Zurich, Switzerland
  • When should locally ablative techniques (radiofrequency ablation, microwave, cryotherapy) be used in patients with unresectable neuroendocrine liver metastases? A systematic review protocol Christos Ceresa, Matriculation No: 05-410-477, University of Zurich, Switzerland

Reviewer Activities

  • Annals of Surgery
  • Journal of Hepatology
  • Surgery
  • Hepatology
  • British Journal of Surgery
  • HPB
  • Journal of Medical Internet Research (JMIR)

Originalarbeiten

  1. Soll C, Wyss P, Gelpke H, Raptis DA, Breitenstein S. Appendiceal stump closure using polymeric clips reduces intra-abdominal abscesses.
    Langenbecks Arch Surg. 2016 Aug;401(5):661-6. doi: 10.1007/s00423-016-1459-3.
    Epub 2016 Jun 13., Impact Factor: 2.14
  2. Giovanni Stracquadanio, Bart Vrugt, Renata Flury, Peter Schraml, Peter Würl, Thomas
    Müller, Uwe Knippschild, Doris Henne-Bruns, Stefan Breitenstein, Pierre-Alain
    Clavien, Rolf Graf, Gareth Bond, and Lukasz Grochola
    ”CD44 SNP rs187115: A novel biomarker signature that predicts survival in resectable
    pancreatic ductal adenocarcinoma”
    Clin Cancer Res. 2016 Jun 9. pii: clincanres.0058.2016., Impact Factor: 8.72
  3. Probst P, Keller D, Steimer J, Gmür E, Haller A, Imoberdorf R, Rühlin M, Gelpke H, Breitenstein S.
    Early combined parenteral and enteral nutrition for pancreaticoduodenectomy – Retrospective cohort analysis
    Ann Med Surg (Lond). 2016 Feb 4;6:68-73. doi: 10.1016/j.amsu.2016.02.002. eCollection 2016 Mar, Impact Factor: 0.63
  4. Biraima M, Adamina M, Jost R, Breitenstein S, Soll C. Long-term results of endoscopic balloon dilation for treatment of colorectal anastomotic stenosis.
    Surg Endosc. 2016 Oct;30(10):4432-7. doi: 10.1007/s00464-016-4762-8. Epub 2016 Feb 19.
    Impact Factor: 3.51
  5. Fischer MA, Raptis DA, Donati OF, Hunziker R, Schade E, Sotiropoulos GC, McCall J, Bartlett A, Bachellier P, Frilling A, Breitenstein S, Clavien PA, Alkadhi H, Patak MA.
    MR imaging features for improved diagnosis of hepatocellular carcinoma in the non-cirrhotic liver: Multi-center evaluation.
    Eur J Radiol. 2015 Oct;84(10):1879-87., Impact Factor: 4.00
  6. Matoori S, Froehlich JM, Breitenstein S, Doert A, Pozdniakova V, Koh DM, Gutzeit A.
    Age dependence of spleen- and muscle-corrected hepatic signal enhancement on hepatobiliary phase gadoxetate MRI.
    Eur Radiol. 2015 Sep 3, Impact Factor: 4.00
  7. G. Lurje, D. A. Raptis, D. Steinemann, I. Amygdalos, P. Kambakamba, H. Petrowsky, M. Lesurtel, A. Zehnder, R. Wyss, P.-A. Clavien, S. Breitenstein
    Cosmesis and body image in patients undergoing single-port vs. conventional laparoscopic cholecystectomy; a multicenter double-blinded randomized controlled trial (SPOCC-trial)
    Ann Surg. 2015, Impact Factor: 7.18
  8. Beck-Schimmer B, Bonvini JM, Schadde E, Dutkowski P, Oberkofler CE, Lesurtel M, DeOliveira ML, Figueira ER, Rocha Filho JA, Auler JO Jr, D’Albuquerque LA, Reyntjens K, Wouters P, Rogiers X, Debaerdemaeker L, Ganter MT, Weber A, Puhan MA, Clavien PA, Breitenstein S. Conditioning with Sevoflurane in Liver Transplantation: Results of a Multicenter Randomized Controlled Trial.
    Transplantation. 2015 Aug;99(8):1606-12., Impact Factor: 3.53
  9. Slankamenac K, Nederlof N, Pessaux P, de Jonge J, Wijnhoven BP, Breitenstein S, Oberkofler CE, Graf R, Puhan MA, Clavien PA.
    The comprehensive complication index: a novel and more sensitive endpoint for assessing outcome and reducing sample size in randomized controlled trials.
    Ann Surg. 2014 Nov;260 (5):757-62; discussion 762-3., Impact Factor: 7.18
  10. Raptis DA, Mettler T, Fischer MA, Patak M, Lesurtel M, Eshmuminov D, de Rougemont O, Graf R, Clavien PA, Breitenstein S.; Managing multicentre clinical trials with open source.
    Inform Health Soc Care. 2014 Mar;39(2):67-80., Impact Factor: 1.15
  11. Donati OF, Hunziker R, Fischer MA, Raptis DA, Breitenstein S, Patak MA.
    MRI for characterization of primary tumors in the non-cirrhotic liver: Added value of Gd-EOB-DTPA enhanced hepatospecific phase.
    Eur J Radiol. 2014 Apr 12., Impact Factor: 2.60
  12. Frilling A, Modlin IM, Kidd M, Russell C, Breitenstein S, Salem R, Kwekkeboom D, Lau WY, Klersy C, Vilgrain V, Davidson B, Siegler M, Caplin M, Solcia E, Schilsky R; Recommendations for management of patients with neuroendocrine liver metastases. Working Group on Neuroendocrine Liver Metastases.
    Lancet Oncol. 2014 Jan;15(1):e8-21., Impact Factor: 24.70
  13. Schadde E, Slankamenac K, Breitenstein S, Lesurtel M, De Oliveira M, Beck-Schimmer B, Dutkowski P, Clavien PA.; Are two-stage hepatectomies associated with more complications than one-stage procedures?
    HPB (Oxford). 2013 Jun;15(6):411-7., Impact Factor: 2.05
  14. Slankamenac K, Beck-Schimmer B, Breitenstein S, Puhan MA, Clavien PA.
    Novel prediction score including pre- and intraoperative parameters best predicts acute kidney injury after liver surgery.
    World J Surg. 2013 Nov;37(11):2618-28., Impact Factor: 2.35
  15. Pfrommer S, Weber A, Dutkowski P, Schäfer NG, Müllhaupt B, Bourquin JP, Breitenstein S, Pestalozzi BC, Stenner F, Renner C, D’Addario G, Graf HJ, Knuth A, Clavien PA, Samaras P.
    Successful Salvage Chemotherapy with FOLFIRINOX for Recurrent Mixed Acinar Cell Carcinoma and Ductal Adenocarcinoma of the Pancreas in an Adolescent Patient. Case Rep Oncol. 2013 Sep 28;6(3):497-503., Impact Factor: 0.00
  16. Burger IA, Schwarz EI, Samarin A, Breitenstein S, Weber A, Hany TF
    Correlation between therapy response assessment using FDG PET/CT and histopathologic tumor regression grade in hepatic metastasis of colorectal carcinoma after neoadjuvant therapy
    Ann Nucl Med.2013Feb; 27(2):177-83., Impact Factor: 1.4
  17. Slankamenac K, Breitenstein S, Beck-Schimmer B, Graf R, Puhan MA, Clavien PA
    Does pharmacological conditioning with the volatile anaesthetic sevoflurane offer protection in liver sugery?
    HPB(Oxford).2012 Dec;14(12):854-62., Impact Factor: 2.05
  18. Tschuor C, Raptis DA, Limani P, Bächler T, Oberkofler CE, Breitenstein S, Graf R
    The value of pancreatic stone protein in predicting acute appendicitis in patients presenting at the emergency department with abdominal pain.
    BMC Gastroenterol. 2012 Oct 25;12:154., Impact Factor 2.11
  19. Oberkofler C, Rickenbacher A, Raptis D, Lehmann L, Villiger P, Buchli C, Grieder F, Decurtins M, Tempia-Caliera A, Demartines N, Hahnloser D, Clavien PA, Breitenstein S
    Perforated left colonic diverticulitis with purulent or fecal peritonitis: Primary Anastomosis or Hartmann’s Procedure? A Multicenter Randomized Clinical Trial
    Annals of Surg, 2012 Nov: 356(5):819-26; discussion 826-7., Impact Factor: 7.18
  20. 1 Beck-Schimmer B, 1 Breitenstein S, Bonvini J, Lesurtel M, Ganter M, Weber A, Puhan M, Clavien PA, (1 First authorship shared)
    Protection of pharmacological postconditioning in liver surgery. Results of a prospective randomized controlled trial.
    Annals of Surg, 2012 Nov;256(5):837-44;discussion 844-5., Impact Factor: 7.18
  21. Steinemann DC, LimaniP, Clavien PA, Breitenstein S
    Internal retractionin Single-port laparoscopic cholecystectomy: Initial experience and learning curve. Minim Invasive Ther Allied Technol. 2012 Oct 4., Impact Factor: 1.33
  22. Clavien PA, Lesurtel M, Bossuyt PM, Gores GJ, Langer B, Perrier A; OLT for HCC Consensus Group (Breitensten S)
    Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus converence report; Lancet Oncol. 2012 jan;13(1):e11-22. Epub2011 Oct 31.
    Impact Factor: 24.70
  23. R Vonlanthen, K Slankamenac, S Breitenstein, M Puhan, D Hahnloser, M Müller, D Hauri,, C Wichmann, R Graf, PA Clavien
    The Impact of Complications on Costs of Major Surgical Procedures – A cost analysis of over 1,200 patients; Ann Surg. 2011 May 10., Impact Factor: 7.47
  24. Fischer MA, Nanz D, Hany T, Reiner CS, Stolzmann P, Donati OF, Breitenstein S, Schneider P, Weishaupt D, von Schulthess GK, Scheffel H. Diagnostic accuracy of whole-body MRI/DWI image fusion for detection of malignant tumours: a comparison with PET/CT.
    Eur Radiol. 2011 Feb;21(2):246-55. Epub 2010 Aug 18., Impact Factor: 4.30
  25. P. Samaras 1, S. Breitenstein 1, S. R. Haile, F. Stenner-Liewen, S. Heinrich, J. Feilchenfeldt, C. Renner, A. Knuth, B Pestalozzi, P.-A. Clavien (1 First authorship shared)
    Selective Intra-arterial Chemotherapy with Floxuridine as Second or Third Line Approach in Patients with Unresectable Colorectal Liver Metastases.
    Ann Surg Oncol. 2011 Jan 5., Impact Factor: 3.94
  26. Petrowsky H 1, Breitenstein S 1, Slankamenac K, Vetter D, Lehmann K, Heinrich S, DeOliveira ML, Jochum W, Weishaupt D, Frauenfelder, Graf R, Clavien PA (1 First authorship shared)
    Effects of Pentoxifylline on Liver Regeneration- A Double-Blinded Randomized Controlled Trial in 101 Patients Undergoing Major Liver Resection
    Ann Surg. 2010 Nov;252(5):813-22, Impact Factor: 7.47
  27. Beatrice Beck-Schimmer 1, Stefan Breitenstein 1, Severin Urech, Elisena De Conno, Moritz Wittlinger, Milo Puhan, Wolfram Jochum, Donat R. Spahn, Rolf Graf, and Pierre-Alain Clavien (1 First athorship shared)
    A Randomized Controlled Trial on Pharmacological Preconditioning in Liver Surgery using a Volatile Anaesthetic.
    Ann Surg. 2008 Dec; 248(6):909-18., Impact Factor: 7.47

Case Reports

  1. Troller R, Soll C, Breitenstein S.
    Glomus tumour of the stomach
    BMJ Case Rep. 2016 Jun 24;2016. pii: bcr2015214135. doi: 10.1136/bcr-2015-214135.
    Impact Factor: 19.967
  2. Beerle C, Soll C, Breitenstein S, Grieder F.
    Spontaneous rupture of an intrahepatic aneurysm of the right hepatic artery caused by segmental arterial mediolysis.
    BMJ Case Rep. 2016 Mar 18;2016. pii: bcr2015214109. doi: 10.1136/bcr-2015-214109.
    Impact Factor: 19.967
  3. Probst P, Knoll SN, Breitenstein S, Karrer U,
    Vertebral discitis after laparoscopic resection rectopexy: A rare differential diagnosis International Journal of Surgery Case Reports
    J Surg Case Rep. 2014 Aug 1;2014(8).
    Impact Factor: 0.50

Reviews

  1. Fan ST, Le Treut YP, Mazzaferro V, Burroughs AK, Olausson M, Breitenstein S, Frilling A.
    Liver transplantation for neuroendocrine tumour liver metastases.
    HPB (Oxford). 2015 Jan;17(1):23-8. Impact Factor: 2.05
  2. E. Arn, R.F. Staerkle, J. Soyka, S. Breitenstein.
    Ileus – Ursachen und Therapieoptionen
    Schweiz Med Forum 2014;14(44):813-819. Impact Factor: 0.00
  3. A. Weimann, S. Breitenstein, J.P. Breuer, S.E. Gabor, S. Holland-Cunz, M. Kemen, F. Längle, N. Rayes, B. Reith, P. Rittler, W. Schwenk, M. Senkal, DGEM Steering Committee Klinische Ernährung in der Chirurgie.
    Der Chirurg 4/2014. Impact Factor: 0.50
  4. Drymousis P, Raptis DA, Spalding D, Fernandez-Cruz L, Menon D, Breitenstein S, Davidson B, Frilling A.; Laparoscopic versus open pancreas resection for pancreatic neuroendocrine tumours: a systematic review and meta-analysis.
    HPB (Oxford). 2014 May;16(5):397-406. Impact Factor: 2.05
  5. Schoke A, Künzli Cornelia, Zehntner C, Hübner Martin, Breitenstein S.
    Optimierung des perioperativen Managements – Enhanced Recovery After Surgery (ERAS.)
    Schweiz Med Forum 2014;14(3):1. Impact Factor: 0.00
  6. Grochola LF, John H, Hess T, Breitenstein S
    Roboterassistierte Chirurgie und 3D-Laparoskopie zum Vorteil der Patienten?
    Schweiz Med Forum 2013;13(3):1. Impact Factor: 0.00
  7. Breitenstein S
    Perioperative Immunonutrition in der Bauchchirurgie
    Schweiz Zeitschrift für Ernährungsmedizin 2012/4. Impact Factor: 0.0
  8. Heinrich S, Richartz G, Breitenstein S, Pestalozzi B, Gubler G
    Das Pankreaskarzinom: Inzidenz, Pathologie, Diagnostik und Therapie
    Schweizerische Zeitschrift für Onkologie 2/2011. Impact Factor: 0.00
  9. Breitenstein S, Reding D, Müllhaupt B, Pestalozzi B
    Kurative Therapiekonzepte beim metastasierten Kolorektalkarzinom, aktuelle chirurgisch-onkologische Strategien.
    Schweizerische Zeitschrift für Onkologie 2/2011. Impact Factor: 0.00

Sonstige Publikationen

  1. Arigoni S, Ignjatovic S, Sager P, Betschart J, Buerge T, Scherrer E, Wachtl J, Tschuor C, Limani P, Puhan MA, Lesurtel M, Raptis DA, Breitenstein S.
    Diagnosis and prediction of neuroendocrine liver metastases: a protocol of six systematic reviews. JMIR Res Protoc. 2014 Apr 28;3(2):e25. doi: 10.2196/resprot.3488.
    Impact Factor: 4.70
  2. Limani P, Tschuor C, Gort L, Balmer B, Gu A, Ceresa C, Raptis DA, Lesurtel M, Puhan M, Breitenstein S.; Nonsurgical Strategies in Patients With NET Liver Metastases: A Protocol of Four Systematic Reviews. JMIR Res Protoc. 2014 Mar 7;3(1):e9. doi: 10.2196/resprot.2893.
    Impact Factor: 4.70
  3. Stump R, Haueis S, Kalt N, Tschuor C, Limani P, Raptis DA, Puhan MA, Breitenstein S.
    Transplantation and surgical strategies in patients with neuroendocrine liver metastases: protocol of four systematic reviews. JMIR Res Protoc. 2013 Dec 23;2(2):e58. doi: 10.2196/resprot.2891.
    Impact Factor: 4.70
  4. Schadde E, Breitenstein S, Clavien PA
    The Swiss HPB Center. Swiss Knife 2011;3.
    Impact Factor: 0.00
  5. Steinemann DC, Raptis DA, Lurje G, Oberkofler CE, Wyss R, Zehnder A, Lesurtel M, Vonlanthen R, Clavien PA, Breitenstein S
    Cosmesis and body image after single-port laparoscopic or conventional laparoscopic cholecystectomy: a multicenter double blinded randomized controlled trial (SPOCC-trial)
    BMC Surg. 2011 Sep 12;11:24. doi: 10.1186/1471-2482-11-24.
    Impact Factor : 1.24

Book Chapters

  1. Kambakamba P, Breitenstein S, Samaras P, Schneider PM, Lurje G (2011)
    Pharmacological advances in metastatic colorectal cancer management
    Future Science Group, London
  2. Dutkowsky P, Breitenstein S, Clavien PA (2011)
    The difficult surgical patients
    Medical Care of the Liver Transplant Patient, 4th edition, Chapter 21
    Blackwell Publishing
  3. Breitenstein S, El Badry A, Clavien PA (2010)
    Uncommon Primary and Metastatic Liver Tumors
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  4. Lehman K, Breitenstein S, Clavien PA (2010)
    From Promethean to Modern Times
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  5. Huizil F, Breitenstein S, Kemeny N (2010)
    Selective Continous Intraarterial Chemotherapy for Liver Tumors
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  6. Breitenstein S, Dimitroulis D, Müllhaupt B (2010)
    Preventing Recurrence of Hepatocellular Carcinoma after Curative Resection
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  7. Breitenstein S, Clavien PA (2010) Introduction: Guidelines for Liver Tumor Treatment
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  8. Breitenstein S, Clavien PA (2010)
    Introduction: Special Tumors and Population and Special Considerations
    Malignant Liver Tumors, 3rd edition, Blackwell Publishing
  9. Book Editor
    Malignant Liver Tumors 3rd edition (2010)
    Blackwell Publishing
    Editor: PA Clavien
    Deputy Editor: S Breitenstein