Leiter und Chefarzt
Klinik für Pneumologie
Leiter Lungentumorzentrum

Funktion
Qualifikationen
Facharzt für Innere Medizin, Pneumologie und Kardiologie
Schwerpunktbezeichnungen:
Internistische Intensivmedizin und Schlafmedizin
Sprachen
Berufserfahrung
seit April 2020
Chefarzt
Klinik für Pneumologie
Kantonsspital Winterthur
2010 – 2020
Leitender Oberarzt
Pneumologische Intensivstation
Universitätsklinikum Tübingen
2007 – 2020
Oberarzt und Leiter
Pneumologie
Medizinische Klinik II
Universitätsklinikum Tübingen
2005 – 2007
Oberarzt und Leiter
Pneumologie
Medizinische Klinik II
Klinikum Heidenheim
2004 – 2005
Stellvertretender Sektionsleiter Pneumologie
Innere Medizin II
Universitätsklinikum Ulm
1993 – 2005
AIP/Assistenzarzt
Innere Medizin II
Universitätsklinikum Ulm
Aus- und Weiterbildung
2013
Habilitation
«Kryoextraktion – Ein neues bronchoskopisches Verfahren zur Diagnostik und Therapie pulmonaler Erkrankungen», Universität Tübingen
2010
Zusatzbezeichnung Schlafmedizin
2009
Medizinische Qualifikation I
MQ I, Kompetenzzentrum für Hochschuldidaktik in Medizin, Baden-Württemberg
2005
Anerkennung der Fakultativen Weiterbildung für Internistische Intensivmedizin
2003
Anerkennung im Teilgebiet Kardiologie
2002
Anerkennung im Teilgebiet Lungen- und Bronchialheilkunde (Pneumologie)
2001
Anerkennung als Facharzt für Innere Medizin
1996
Promotion
«Wirksamkeit von Nitraten bei Patienten mit chronischer Herzinsuffizienz auf der Grundlage einer koronaren Herzerkrankung, die gleichzeitig eine Therapie mit dem ACE-Hemmer Captopril und Diuretika erhalten»
1995
Approbation als Arzt
1986 – 1993
Medizinstudium
Universität Ulm
Originalarbeiten seit 2013
- Nintedanib in patients with progressive fibrosing interstitial lung diseases-subgroup analyses by interstitial lung disease diagnosis in the INBUILD trial: a randomised, double-blind, placebo-controlled, parallel-group trial.
Wells AU, Flaherty KR, Brown KK, Inoue Y, Devaraj A, Richeldi L, et al.
The Lancet Respiratory medicine. 2020. - Evaluation of Efficacy of a New Cryoprobe for Transbronchial Cryobiopsy: A Randomized, Controlled in vivo Animal Study.
Hetzel J, Linzenbold W, Boesmueller H, Enderle M, Poletti V.
Respiration. 2020:1-9. - Use of 3-D navigation to target the site of autologous blood installation for lung volume reduction in bullous emphysema.
Hetzel J, Boeckeler M, Lewis RA, Horger M, Haentschel M.
Chronic respiratory disease. 2020;17:1479973120903556. - Cryobiopsy increases the EGFR detection rate in non-small cell lung cancer.
Haentschel M, Boeckeler M, Ehab A, Wagner R, Spengler W, Steger V, et al.
Lung cancer (Amsterdam, Netherlands). 2020;141:56-63. - Confocal Laser Endomicroscopy as a Guidance Tool for Transbronchial Lung Cryobiopsies in Interstitial Lung Disorder.
Wijmans L, Bonta PI, Rocha-Pinto R, de Bruin DM, Brinkman P, Jonkers RE, et al.
Respiration. 2019;97(3):259-63. - The effect of intraparenchymal blood patching on the rate of pneumothorax in patients undergoing percutaneous CT-guided core biopsy of the lung.
Perl RM, Risse E, Hetzel J, Bosmuller H, Kloth C, Fritz J, et al.
European journal of radiology. 2019;116:14-20. - Prediction of response to endobronchial coiling based on morphologic emphysema characterization of the lung lobe to be treated and the ipsilateral non-treated lobe as well as on functional computed tomography-data: correlation with clinical and pulmonary function.
Kloth C, Thaiss WM, Fritz J, Nikolaou K, Beer M, Hetzel J, et al.
Journal of thoracic disease. 2019;11(1):93-102. - Bleeding risk of transbronchial cryobiopsy compared to transbronchial forceps biopsy in interstitial lung disease – a prospective, randomized, multicentre cross-over trial.
Hetzel J, Eberhardt R, Petermann C, Gesierich W, Darwiche K, Hagmeyer L, et al.
Respir Res. 2019;20(1):140. - Reverse rendezvous with endoscopic retrograde cholangiography and percutaneous transhepatic cholangio drainage: who meets whom?
Goetz M, Fisch J, Hetzel J, Grozinger G.
Endoscopy. 2019;51(3):E47-e8. - Nintedanib in Progressive Fibrosing Interstitial Lung Diseases.
Flaherty KR, Wells AU, Cottin V, Devaraj A, Walsh SLF, Inoue Y, et al.
N Engl J Med. 2019;381(18):1718-27. - Endobronchial Coils Versus Lung Volume Reduction Surgery or Medical Therapy for Treatment of Advanced Homogenous Emphysema.
Marchetti N, Kaufman T, Chandra D, Herth FJ, Shah PL, Slebos DJ, et al.
Chronic obstructive pulmonary diseases (Miami, Fla). 2018;5(2):87-96. - Results of quantitative chest-CT in chronic pulmonary graft-vs.-host disease (cGvHD) 3 years after allogeneic stem cell transplantation.
Kloth C, Thaiss WM, Hetzel J, Bier G, Wirths S, Nikolaou K, et al.
Journal of thoracic disease. 2017;9(8):2521-7. - A new functional method to choose the target lobe for lung volume reduction in emphysema – comparison with the conventional densitometric method.
Hetzel J, Boeckeler M, Horger M, Ehab A, Kloth C, Wagner R, et al.
International journal of chronic obstructive pulmonary disease. 2017;12:2621-8. - Bronchial Artery Embolization in Hemoptysis: 10-Year Survival and Recurrence-Free Survival in Benign and Malignant Etiologies – A Retrospective Study.
Syha R, Benz T, Hetzel J, Spengler W, Kohlhaufl MJ, Gatidis S, et al.
RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin. 2016;188(11):1061-6. - Impact of endobronchial coiling on segmental bronchial lumen in treated and untreated lung lobes: Correlation with changes in lung volume, clinical and pulmonary function tests.
Kloth C, Thaiss WM, Hetzel J, Ditt H, Grosse U, Nikolaou K, et al.
European radiology. 2016;26(7):2176-83. - Segmental bronchi collapsibility: computed tomography-based quantification in patients with chronic obstructive pulmonary disease and correlation with emphysema phenotype, corresponding lung volume changes and clinical parameters.
Kloth C, Thaiss WM, Ditt H, Hetzel J, Schulen E, Nikolaou K, et al.
Journal of thoracic disease. 2016;8(12):3521-9. - Quantitative chest CT analysis in patients with systemic sclerosis before and after autologous stem cell transplantation: comparison of results with those of pulmonary function tests and clinical tests.
Kloth C, Maximilian Thaiss W, Preibsch H, Mark K, Kotter I, Hetzel J, et al.
Rheumatology (Oxford, England). 2016;55(10):1763-70. - Cross-Sectional Survey on Bronchoscopy in Germany–The Current Status of Clinical Practice.
Hautmann H, Hetzel J, Eberhardt R, Stanzel F, Wagner M, Schneider A, et al.
Pneumologie (Stuttgart, Germany). 2016;70(2):110-6. - A New Tool for Transbronchial Cryobiopsies in the Lung: An Experimental Feasibility ex vivo Study.
Franke KJ, Linzenbold W, Nuessle D, Enderle M, Boesmueller H, Nilius G, et al.
Respiration. 2016;91(3):228-34. - Bronchoscopic Coil Treatment for Patients with Severe Emphysema: A Meta-Analysis.
Slebos DJ, Hartman JE, Klooster K, Blaas S, Deslee G, Gesierich W, et al.
Respiration. 2015;90(2):136-45. - Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV).
Schwabbauer N, Berg B, Blumenstock G, Haap M, Hetzel J, Riessen R.
BMC anesthesiology. 2014;14:66. - Diagnostic yield of transbronchial cryobiopsy in interstitial lung disease: a randomized trial.
Pajares V, Puzo C, Castillo D, Lerma E, Montero MA, Ramos-Barbon D, et al.
Respirology (Carlton, Vic). 2014;19(6):900-6. - Impact of endobronchial coiling for lung volume reduction on pulmonary volume and attenuation: preinterventional and postinterventional computed tomography-quantification using separate lobe measurements.
Grosse U, Hetzel J, Gundel L, Gatidis S, Syha R, Schabel C, et al.
Journal of computer assisted tomography. 2014;38(5):779-85. - Cryorecanalization for in-stent recanalization in the esophagus.
Goetz M, Malek NP, Kanz L, Hetzel J.
Gastroenterology. 2014;146(5):1168-70. - Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial.
Deslee G, Klooster K, Hetzel M, Stanzel F, Kessler R, Marquette CH, et al.
Thorax. 2014;69(11):980-6. - Does volume perfusion computed tomography enable differentiation of metastatic and non-metastatic mediastinal lymph nodes in lung cancer patients? A feasibility study.
Spira D, Wecker M, Spira SM, Hetzel J, Spengler W, Sauter A, et al.
Cancer imaging : the official publication of the International Cancer Imaging Society. 2013;13(3):323-31. - Assessment of tumor vascularity in lung cancer using volume perfusion CT (VPCT) with histopathologic comparison: a further step toward an individualized tumor characterization.
Spira D, Neumeister H, Spira SM, Hetzel J, Spengler W, von Weyhern CH, et al.
Journal of computer assisted tomography. 2013;37(1):15-21. - Correlation between [18F]FDG PET/CT and volume perfusion CT in primary tumours and mediastinal lymph nodes of non-small-cell lung cancer.
Sauter AW, Spira D, Schulze M, Pfannenberg C, Hetzel J, Reimold M, et al.
European journal of nuclear medicine and molecular imaging. 2013;40(5):677-84.
Internationale Richtlinien und Expert Statements
- Transbronchial Cryobiopsy for the Diagnosis of Interstitial Lung Diseases: CHEST Guideline and Expert Panel Report.
Maldonado F, Danoff SK, Wells AU, Colby TV, Ryu JH, Liberman M, et al.
Chest. 2019. - Transbronchial Cryobiopsies for the Diagnosis of Diffuse Parenchymal Lung Diseases: Expert Statement from the Cryobiopsy Working Group on Safety and Utility and a Call for Standardization of the Procedure.
Hetzel J, Maldonado F, Ravaglia C, Wells AU, Colby TV, Tomassetti S, et al.
Respiration. 2018;95(3):188-200.
Übersichtsarbeiten
- Excessive Dynamic Airway Collapse.
Perl RM, Steger V, Hetzel J, Horger M.
RoFo: Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin. 2019;191(4):269-73. - Allergic bronchopulmonary aspergillosis (ABPA).
Baumgartner K, Kubler J, Haap M, Hetzel J, Horger M.
RoFo: Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin. 2019. - Transbronchial Lung Cryobiopsy in Interstitial Lung Diseases: Best Practice.
Colella S, Haentschel M, Shah P, Poletti V, Hetzel J.
Respiration. 2018;95(6):383-91. - Controlled Pressure: The Solution for a High-Pressure Situation – Aetiology and Techniques for Control of Airway Haemorrhage.
Singh S, Hetzel J, Shah PL.
Respiration. 2017;93(6):398-400. - Transbronchial Cryobiopsy in Diffuse Parenchymal Lung Disease: Need for Procedural Standardization.
Poletti V, Hetzel J.
Respiration. 2015;90(4):275-8. - Lung volume reduction by coils and valves and the role of CT-imaging.
Horger M, Grosse U, Hetzel J, Ioanoviciu SD.
RoFo: Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin. 2014;186(10):909-13.
Briefe
- Before Freezing Out Cryobiopsy, We Need to Thaw Out Flaws in the Diagnosis of Interstitial Lung Disease.
Maldonado F, Wells A, Danoff S, Colby T, Ryu J, Poletti V, et al.
American journal of respiratory and critical care medicine. 2019;200(7):937-8. - Transbronchial Cryobiopsy: A Cautionary Tale and Opportunities for Improvement.
Lentz RJ, Argento AC, Rickman OB, Ryu JH, Poletti V, Hetzel J, et al.
Annals of the American Thoracic Society. 2017;14(7):1230-1.
Fallberichte
- Tracheobronchial Polyposis after Inhalation Trauma.
Heitmann JS, Federmann B, Hetzel J, Hantschel M.
Anesthesiology. 2020;132(1):157. - Incidental lung volume reduction following fulminant pulmonary hemorrhage in a patient with severe emphysema.
Hetzel J, Spengler W, Horger M, Boeckeler M.
Lung. 2015;193(3):429-32.
Buchbeiträge
- Kapitel 9 Pulmonale Manifestationen von Vaskulitiden
Michael Kreuter, Ulrich Costabel, Felix Herth, Detlef Kirsten
Seltene Lungenerkrankungen. Springer-Verlag, 23.02.2016 – 448 Seiten, ISBN 978-3662484180