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Portrait von Prof. Dr. med. et Dr. sc. nat. Bruno Fuchs

Prof. Dr. med. et Dr. sc. nat. Bruno Fuchs

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Funktion

Chefarzt, Leiter Orthopädische Tumorchirurgie
Klinik für Orthopädie und Traumatologie
Leiter Sarkomzentrum

Qualifikationen

Facharzt  für Orthopädische Chirurgie und Traumatologie des Bewegungsapparates

Icon Tumorzentrum Winterthur Ksw
Tumorzentrum Winterthur
Im Tumorzentrum bündeln Spezialistinnen und Spezialisten ihr Wissen und ihre Erfahrung zur Behandlung von Krebs.
Mehr erfahren
Icon Orthopaedie Traumatologie Ksw
Orthopädie und Traumatologie
Unsere acht Fachteams bieten praktisch das gesamte Spektrum der orthopädischen und der traumatologischen Chirurgie an.
Mehr erfahren

Ausbildungsstellen und klinische Tätigkeit

seit 2019
Chair Swiss Sarcoma Network

seit 2018
Gründungsmitglied und Leiter Sarkomzentrum
Kantonsspital Winterthur

seit 2017
Chefarzt und Leiter
Orthopädische Tumorchirurgie
Kantonsspital Winterthur

seit 2017
Gründungsmitglied und Senior Consultant
Sarkomboard und Sarkomzentrum
Universitätsspital Zürich

2012 – 2017
Gründungsmitglied und Leiter
Sarkomzentrum und Konsiliarius
Universitätsspital Zürich

2005 – 2016
Leiter
Orthopädische Forschung
Universitätsklinik Balgrist

2005 – 2016
Leitender Arzt
Tumorchirurgie
Universitätsklinik Balgrist

2004
Oberarzt
Universitätsklinik Balgrist

2000 – 2004
Graduate School in Biomedical Sciences
Molecular and Tumor Biology
Mayo College of Medicine, Rochester USA

1998 – 2000
Fellowship
Musculoskeletal Oncology
Mayo Clinic, Rochester USA

1996 – 1998
Assistenzarzt
Orthopädie und Traumatologie
Universitätsklinik Balgrist und Inselspital Bern

1993 – 1995
Assistenzarzt
Allgemeine Chirurgie und Neurochirurgie


Spezialisierung

Abklärung und Behandlung von Knochen- und Weichteiltumoren am Muskuloskelettalen System:

  • Begleitung und Führung von Patienten mit Knochen- und Weichteiltumoren
  • Koordination und Management von Patienten innerhalb der Disziplinen im Rahmen des Sarkomboards
  • Durchführung von Biopsien jeglicher Art in Zusammenarbeit mit den Radiologen
  • Operative Entfernung sowie Rekonstruktion von gut- und bösartigen Knochentumoren des Muskuloskelettalen Systems (inkl. Osteosarkom, Ewing’s Sarkom, und Chondrosarkom) von Kindern und Erwachsenen
  • Operative Entfernung und wenn nötig Rekonstruktion von gut- und bösartigen Tumoren der Weichteile von Kindern und Erwachsenen (Muskelgewebe, Fettgewebe, Gefässe und Nerven etc) des Muskuloskelettalen Systems (inkl. pleomorphe Sarkome; Liposarkome etc)

Ausbildung

2004
Abschluss (Tumor-)Molekularbiologie Studium
Mayo Graduate School

1997
USLME I / II
United States Medical Licensing Examination

1992
Abschluss Medizin Studium
Medizinische Fakultät Zürich


Akademische Stellung

Professor


Akademische Aktivitäten

  • Drittmittel Grants
    Insgesamt mehr als 10 Mio sFr (u.a. von EuroNanoMed)
  • Schweizerischer Nationalfonds (SNF)
  • HSM Programm for Muskuloskelettale Onkologie des Kantons Zürich (Zürcher Krebsliga)
  • Reviewer für SNF (Schweizerische, Deutsche und Zürcher Krebsliga, sowie mehr als 40 internationale perr-reviewed Journals seit 2008 (u.a. Nature, Cancer Research; J Cell Mol Medicine; J Nuclear Medicine)

Präsentationen seit 2008

  • 132 an nationalen Meetings
  • 51 an internationalen Meetings
  • 59 eingeladene Präsentationen

Diplome und Ernennungen

2017
Professor
Universität Zürich

2010
Extraordinarius
Medizinische Fakultät
Universität Zürich

2005
Assistenzprofessor
Medizinische Fakultät
Universität Zürich

2005
Facharzt FMH
Orthopädische Chirurgie und Traumatologie des Bewegungsapparates

2004
PhD Dissertation
Biomedical Sciences and Tumor Biology
Mayo Graduate School, Mayo College of Medicine, Rochester USA

2000
Assistant Professor
Department of Orthopedics
Mayo Clinic, Rochester USA

1999
Instructor
Department of Orthopedics
Mayo Clinic, Rochester USA

1993
MD Dissertation
Universität Zürich


Preise/Ehrungen

2015
Maurice E.Müller Research Prize
presented at the 75th Meeting
For the study: „Prognostic Value and In-vitro Biological Relevance of Neuropilin 1 and Neuropilin-2 in Osteosarcoma“
Swiss Society of Orthopedic Surgeons (SwissOrthopaedics)
Basel, Switzerland

2012
Basic Research Award 2012
For the study on: „Cyr61 indicates Poor Survival in Osteosarcoma Patients and Promotes Intratibial Xenograft Primary Tumor Growth and Lung Metastasis in Mice“
Swiss Bone and Mineral Research Society (SBMS)

2011  
Travelling Fellowship Award (student) of the International Skeletal Society (ISS)
For the Special Scientific Session and for the study: „Evaluation of the Diagnostic Power of Six PET Tracers in an Orthotopic Intratibial Osteosarcoma Mouse Model“
Meeting in San Diego, CA USA

2008 
Best Presentation at the 14th Annual Meeting
For the study: „Cyr61 Expression in Human Osteosarcoma Correlates with Tumor Metastasis“
Swiss Bone and Mineral Society
Davos, Switzerland

2008  
The 2008/2009 Limb Preservation Foundation Pilot Research Grant Award
For the study: „Assessment of Intraarterial Chemotherapy in an Osteosarcoma Mouse Model of Spontaneous Metastasis.“
The Limb Preservation Foundation, Denver, USA

2007  
1st Place and Best “First Time Presentation of a Resident”
For the study: „Rare Diaphyseal Lesions of the Ulna: Surgical Treatment Considerations“
Swiss Orthopedic Society
Montreux, Switzerland

2004   
EW.Johnson Award of the Mid-America Orthopaedic Association
For the study: „Operative Management of Sacro-coccygeal Chordoma“

2003  
Fellowship Award (EFORT-ZIMMER AWARD)
For Orthopaedic Surgery
Offered by the European Federation of National Associations of Orthopaedics and Traumatology and Zimmer
Young Investigator Career Development

2002  
One-Year-Scholarship
Swiss Society of Orthopedic Surgeons

2001 
One-Year-Scholarship
Swiss Society of Orthopedic Surgeons

2001  
Jubiläumspreis
Swiss Radiological Society
Painful Lumbar Disc Derangement: Relevance of Endplate Abnormalities at MR imaging

1999
Patrick J.KELLY Basic Research Award (special fellows category) of the Department of Orthopedics
For the study: „Development of Genetic Landmarks for Comparative Expression Genomics of Osteogenic Sarcoma“
Mayo Clinic and Foundation

1998   
Charles S. NEER Award (Clinical Category)
for the study: „The Clinical and Structural Results of Direct Repair of Massive Tears of the Rotator Cuff“
American Society of Shoulder and Elbow Surgeons ASES


Mitgliedschaften

  • SwissOrthopaedics
  • FMH (Foederatio Medici Helveticorum)
  • Mayo Clinic Orthopedic Alumni Association
  • IVINS Society; FH-Sim Society
  • CTOS (Connective Tissue Oncology Society)
  • MSTS (Musculoskeletal Tumor Society)
  • EMSOS (European Musculoskeletal Oncology Society)
  • ISS (International Skeletal Society)
  • Swiss MD-PhD Society

(Stand Oktober 2022: H-index 36; citations 5225; Google scholar)

  1. B. Fuchs, D. Weishaupt, M. Zanetti, J. Hodler, C. Gerber.  Fatty degeneration of
    the muscles of the rotator cuff:  Assessment by CT versus MR Imaging.
    J Shoulder Elbow Surg  Vol 6 Nov-Dec, 8:599-605, 1999
  2. B. Fuchs, K. Zhang, MG Rock, ME Bolander, G. Sarkar.  Repeat cDNA synthesis and RT-PCR with the same source of RNA.
    Molecular Biotechnology Vol 12:231-235, 1999
  3. B. Fuchs, K. Zhang, MG Rock, ME Bolander, G. Sarkar.  High temperature
    cDNA synthesis by AMV reverse transcriptase improves the specificity of PCR.
    Molecular Biotechnology Vol 12:237-240, 1999
  4. B. Fuchs, B. Jost, C. Gerber.  Posterior Inferior Capsular Shift for the Treatment of Recurrent, Voluntary Posterior Shoulder Subluxation.
    J Bone Joint Surg-Am. 82A:16-25, 2000
  5. C. Gerber, B. Fuchs, J. Hodler.  The Results of the Repair of Massive Tears of the Rotator Cuff.
    J Bone Joint Surg-Am. 82A: 505-515, 2000
  6. B. Fuchs, K.Zhang, ME Bolander, G. Sarkar.  Identification of differentially expressed genes by mutually subtracted RNA fingerprinting.
    Analytical Biochem Nov 286(1):91-98, 2000
  7. B. Fuchs, K.Zhang, ME Bolander, G. Sarkar.  Differential mRNA fingerprinting by preferential amplification of coding sequences.
    Gene   258:155-163, 2000
  8. B. Fuchs, AM Davis, JS. Wunder, RS Bell, BA Masri, B. Isler, R. Turcotte, MG  Rock.  Sciatic nerve resection in the thigh: A functional evaluation
    Clin Orthop  382: 34-41, 2001
  9. D. Weishaupt, M.Zanetti, Hodler J, K.Min, B. Fuchs, CW Pfirrmann, N. Boos. Painful lumbar disk derangement: Relevance of endplate abnormalities at MR imaging.
    Radiology 218(2):420-427, 2001
  10. B.Fuchs, K.Zhang, A.Schabel, ME Bolander, G.Sarkar: Identification of twenty-two candidate genetic markers for osteogenic sarcoma
    Gene  278:245-252, 2001
  11. B.Fuchs, MJ.Yaszemski, FH.Sim: Resection of the Posterior Pelvis and Lumbar Spine for Sarcoma.
    Clin Orthop  397:12-18, 2002
  12. Todd LT, Yaszemski MJ, Currier BL, Fuchs B, Kim CW, MB.Dekutoski, Sim FH. Bowel and Bladder Function following Major Sacral Resection.
    Clin Orthop 397:36-39, 2002
  13. Talac R, Yaszemski MJ, Currier BL, Fuchs B, Dekutoski MB, Kim CW, Sim FH. Relationship between surgical margins and local recurrence in sarcomas of the spine.
    Clin Orthop 397:127-32, 2002
  14. B.Fuchs, DJ.Pritchard. Etiology of Osteosarcoma.*
    Clin Orthop 397:40-52, 2002 
    *specifically noted as highlight in editorial comment: Clin Orthop 397:2, 2002
  15. B.Fuchs, MI.O’Connor, KR.Kaufman, DJ Padgett, FH.Sim. Iliofemoral arthrodesis and Pseudarthrosis: A functional long-term outcome evaluation.
    Clin Orthop 397:29-35, 2002
  16. K.Zhang, N.Dion, B.Fuchs, T.Damron, S.Gitelis, R.Irwin, M.O’Connor, H.Schwartz, SP.Scully, MG.Rock, ME.Bolander, G.Sarkar. The hSEP1 is a novel candidate tumor suppressor gene in osteogenic sarcoma.
    Gene  298:121-127, 2002
  17. B.Fuchs, U.Knothe, R.Hertel, R.Ganz. Femoral Osteotomy and Iliac Graft Vascularization for Femoral Head Osteonecrosis.
    Clin Orthop 412:84-93, 2003
  18. B.Fuchs, C.Inwards, R.Janknecht. Upregulation of the matrix metalloproteinase- gene by the Ewing’s sarcoma associated EWS-ER81 and EWS-Fli1 oncoproteins, c-Jun and p300.
    FEBS Letters  553:104-108, 2003
  19. B.Fuchs, R.Valenzuela, FH.Sim. Pathologic Fracture as a Complication in the Treatment of Ewing’s Sarcoma.
    Clin Orthop 415: 25-30, 2003
    *specifically highlighted in editorial comment: Clin Orthop 415:2-3, 2003
  20. B.Fuchs, BR.Kotajarvi, K.Kaufman, FH.Sim. Functional Outcome of Patients with Rotationplasty about the knee.
    Clin Orthop 415: 52-58, 2003
    *specifically highlighted in editorial comment: Clin Orthop 415:2-3, 2003
  21. B.Fuchs, R.Valenzuela, CS. Arndt, IA.Petersen, FH.Sim. Ewing’s sarcoma and the Development of Secondary Malignancies.
    Clin Orthop 415: 82-89, 2003
    *specifically highlighted in editorial comment: Clin Orthop 415:2-3, 2003
  22. B.Fuchs, R.Valenzuela, C.Inwards, FH.Sim, MG.Rock: Complications in Long-term Survivors of Ewing’s sarcoma.
    Cancer  98(12):2687-92, 2003
  23. B.Fuchs, C.Inwards, R.Janknecht: VEGF expression is Upregulated by EWS-ETS Oncoproteins and Sp1 and may Represent an Independent Predictor of Survival in Ewing’s sarcoma.
    Clin Cancer Res 10:1344-1353, 2004
  24. EY.Chao, B.Fuchs, CM.Rowland, DM.Illstrup, DJ.Pritchard, FH.Sim. Long-term Results of Segmental Prosthesis Fixation by Extra-Cortical Bone Bridging and Ingrowth.
    J Bone Joint Surg Am 86:948-955, 2004
  25. B.Fuchs, FH.Sim. Rotationplasty about the Knee: Surgical Technique and Anatomical Considerations.
    Clin Anat 17(4):345-353, 2004
  26. B.Fuchs, C.Inwards, SP.Scully, R.Janknecht. hTERT is Highly Expressed in Ewing’s Sarcoma and Activated by EWS-ETS Oncopoteins.
    Clin Orthop 426:64-68, 2004
  27. I.Dickey, P.Rose, B.Fuchs, D., Okuno, S, Wold L, FH.Sim, SP.Scully. Dedifferentiated Chondrosarcoma: Updated Ouctomes with Current Treatment Approaches.
    J Bone Joint Surg 86-Am 11:2412-2418, 2004
  28. FH.Sim, B.Fuchs, DJ.Jacofsky. Innovations in Musculoskeletal Oncologic Surgery over the Year 2000.
    Chir Organi Mov 89(3):181-190, 2004
  29. B. Fuchs, RT.Trousdale, MG. Rock.  Solitary Bony Metastasis from Renal Cell Carcinoma: Significance of Surgical Treatment.
    Clin Orthop 431:187-192, 2005
  30. B.Fuchs, SP.Steinmann, AT.Bishop: Free Vascularized Corticoperiosteal Bone Graft for the Treatment of Persistent Nonunion of the Clavicle.
    J Shoulder Elbow Surg 14(3):264-268, 2005
  31. B.Fuchs, MI.O’Connor, DJ.Padget, KR.Kaufman, FH.Sim: Arthrodesis of the Shoulder after Tumor Resection
    Clin Orthop 436:202-207, 2005
  32. B.Fuchs, ID.Dickey, MJ.Yaszemski, C.Inwards, FH.Sim. Operative Management of Sacral Chordoma
    J Bone Joint Surg 87-Am 10:2211-2216, 2005
  33. ID.Dickey, RR.Hugate, B.Fuchs, MJ.Yaszemski, FH.Sim: Reconstruction after Total Sacrectomy: Early Experience with a New Surgical Technique
    Clin Orthop 438:42-50, 2005
  34. B.Fuchs, RJ.Spinner, MG.Rock: MPNST Malignant Peripheral Nerve Sheath Tumors: An update
    J Surg Orthop Adv 14:168-174, 2005
  35. B.Fuchs, MK.Gilbart, J.Hodler, C.Gerber: The Clinical and Structural Results of Open Repair of an Isolated One-tendon Tear of the Rotator Cuff.
    J Bone Joint Surg 88-Am 2:309-316, 2006
  36. SF.Fucentese, A.von Roll, PP.Koch, DR.Epari, B.Fuchs, PB.Schoettle: The Patella Morphology in Trochlear Dysplasia – A Comparative MRI Study.
    Knee 13:145-150, 2006
  37. A. Srivastava*, B.Fuchs*, K.Zhang, M.Ruan, C.Halder, E.Mahlum, K.Weber, ME.Bolander, G.Sarkar: High WT1 Expression is Associated with poor survival of patients with Osteogenic sarcoma metastasis.
    Clin Cancer Res 12(14): 4237-4243, 2006*Co-First-Authorship
  38. C.Ossendorf, B.Fuchs, P.Koch: Femoral Stress Fracture after Computer Navigated Total Knee Arthroplasty.
    Knee 13(5):397-399, 2006
  39. F.Mueller, B.Fuchs, B.Kaser: Comparative Biology of Human and Canine Osteosarcoma
    Anticancer Res 27(1A):155-164, 2007
  40. D.Walters, R.Muff, B.Langsam, P.Gruber, W.Born, Fuchs B: Taurolidine: A novel Anti-neoplastic Agent induces Apoptosis of Osteosarcoma Cell Lines.
    Invest New Drugs 25(4):305-12, 2007
  41. B.Fuchs, E.Mahlum, C.Halder, A.Maran, M.Yaszemski, B.Bode, M.Bolander, G.Sarkar: High Expression of Tumor Endothelial Marker 7 is associated with Metastasis and poor Survival of Patients with Osteogenic Sarcoma.
    Gene  399(2):137-143,  2007
  42. R.Muff, N.Nigg, P.Gruber, D.Walters, W.Born, B.Fuchs: Altered Morphology, Nuclear Stability and Adhesion of Highly Metastatic Derivatives of Osteoblast-like SaOS-2 Osteosarcoma Cells
    Anticancer Res  27(6B): 3973-3979, 2007
  43. N.Bodmer, DK.Walters, B.Fuchs: Pemetrexed, a Multitargeted Antifolate Drug, Demonstrates Lower Efficacy in Comparison to Methotrexate against Osteosarcoma Cell Lines.
    Pediatr Blood Cancer 50(4):905-8, 2008
  44. K.Husmann, R.Muff, W.Born, ME.Bolander, G.Sarkar, B.Fuchs: Cathepsins and Osteosarcoma: Expression Analysis identifies Cathepsin K as a Prognostic Indicator of Metastasis.
    Mol Carcinog 47:66-73, 2008
  45. HA.Ruediger, B.Fuchs, A.von Campe, C.Gerber: Measurements of Shoulder Mobility by Patient and Surgeon Correlate Poorly: A Prospective Study.
    J Shoulder Elbow Surg 17(2):255-60, 2008
  46. DK.Walters, P.Steinmann, B.Langsam, S.Schmutz, W.Born, B.Fuchs: Identification of Potential Chemoresistance Genes in Osteosarcoma
    Anticancer Res 28:673-80, 2008
  47. DK.Walters, R.Muff, B.Langsam, W.Born, B.Fuchs: Cytotoxic Effects of Curcumin on Osteosarcoma Cell Lines
    Invest New Drugs 26:289-97, 2008
  48. B.Fuchs, C.Ossendorf, T.Leerapun, FH.Sim: Intercalary Segmental Reconstruction for Bone Defects.
    Europ J Surgical Oncol 34(12):1271-6, 2008
  49. B.Fuchs, M.Zumstein, F.Regenfelder, P.Steinmann, T.Fuchs, K.Husmann, J.Hellermann, B.Jost, J.Hodler, W.Born, C.Gerber. Upregulation of alpha-skeletal muscle actin and myosin heavy polypeptide gene products in degenerating rotator cuff muscles.
    J Orthop Res 26:1007-11, 2008
  50. C.Ossendorf, GM.Studer, B.Bode, B.Fuchs: Sclerosing Epithelioid Fibrosarcoma: Case Presentation and a Systematic Review
    Clin Orthop Rel Res 466:1485-1491, 2008
  51. S.Schmutz, T.Fuchs, F.Regenfelder, P.Steinmann, M.Zumstein, B.Fuchs. Expression of Atrophy mRNA relates to Tendon Tear Size in Supraspinatus Muscle.
    Clin Orthop Rel Res  467(2):457-464, 2009
  52. E.Frey, F.Regenfelder, P.Sussmann, M.Zumstein,  C.Gerber, W.Born, B.Fuchs: Adipogenic and Myogenic Gene Expression in Rotator Cuff Muscle of the Sheep after Tendon Tear.
    J Orthop Res 27(4):504-509, 2009
  53. B.Fuchs, N.Hoekzema, D.Larson, C.Inwards, FH.Sim: Osteosarcoma of the Pelvis: Outcome Analysis of Surgical Treatment.
    Clin Orthop Rel Res 467(2):510-518, 2009
  54. J.Yuan, C.Ossendorf, JP.Szatkowski, J.Bronk, A.Maran, M.Yaszemski, ME.Bolander, G.Sarkar, B.Fuchs: Osteoblastic and Osteolytic Human Osteosarcomas can be studied with a New Xenograft Mouse Model Producing Spontaneous Metastases
    Cancer Invest  27(4):435-42, 2009
  55. R.Hudek, S.Schmutz, F.Regenfelder, B.Fuchs, PP.Koch. Novel Measurement Technique of the Tibial Slope on Conventional MRI.
    Clin Orthop Rel Res 467:2066-72, 2009
  56. B.Fuchs, W.Born. Molecular and Cellular Mechanisms of Osteosarcoma Metastasis: Current Knowledge and Perspectives (Review)
    Current Orthopaedic Practice 20(6):593-597, 2009
  57. C.Halder, C.Ossendorf, A.Maran, M.Yaszemski, B.Fuchs, G.Sarkar. Preferential Expression of the Secreted and the Membrane Forms of Tumor Endothelial Marker 7 Transcripts in Osteosarcoma.
    Anticancer Res 29(11):4317-22, 2009
  58. C. Ossendorf, GU.Exner, B.Fuchs. A New Incision Technique to Reduce Tibiofemoral Mismatch in Rotationplasty.
    Clin Orthop Rel Res 468:1264-1268, 2010
  59. P.Zwolak, P.Kuehnel, B.Fuchs. Extra-articular Knee Resection for Sarcomas with Preservation of the Extensor Mechanism: Surgical Considerations and Review of Cases
    Clin Orthop Rel Res 469:251-256, 2011
  60. A.Krieg, F.Hefti, B.Speth, L.Guillou, G.Jundt, U.Exner, A.v.Hochstetter, M.Cserhati, B.Fuchs, E.Moushine, A.Kaelin, F.Klenke, K.Siebenrock. Synovial Sarcomas usually Metastasize after  > five Years: A Multicenter, Retrospective Analysis with Minimum Followup of 10 Years for Survivors
    Annals of Oncology 22(2):458-67, 2011
  61. PP.Koch, B.Fuchs, DC. Meyer, SF.Fucentese. Closing Wedge Patellar Osteotomy in Combination with Trochleoplasty.
    Acta Orthop Belg 77(1):116-121, 2011
  62. MJE. Arlt, IJ. Banke, DK. Walters, G. Puskas, P. Steinmann, R. Muff, W. Born, B. Fuchs. LacZ Transgene Expression in the Subcutaneous Dunn / LM8 Osteosarcoma Mouse Model Allows for the Identification of Micrometastasis
    J Orthop Res 29(6):938-46, 2011
  63. R.Hudek, B.Fuchs, F.Regenfelder, PP.Koch. Is Non-contact ACL Injury Associated with the Posterior Tibial and Meniscal Slope?
    Clin Orthop Rel Res 469:2377-84, 2011
  64. B.Fuchs: Current Trends in Musculoskeletal Oncology
    Leading Opinions Orthopädie & Rheumatologie  3:22-24, 2011
  65. P.Steinmann, DK.Walters, MA.Arlt, I.Banke, U.Ziegler, B.Langsam, J.Arbiser, R.Muff, W.Born, B.Fuchs: Antimetastatic Activity of Honokiol in Osteosarcoma.
    Cancer 118(8):2117-27, 2012
  66. A.Sabile, M.Arlt, R.Muff, B.Bode, B.Langsam, J.Bertz, T.Jentzsch, G.Puskas, W.Born, B.Fuchs: Cyr61 indicates Poor Survival in Osteosarcoma Patients and Promotes Intratibial Xenograft Primary Tumor Growth and Lung Metastasis in Mice.
    J Bone Mineral Res 27(1):58-67, 2012
  67. MJE. Arlt, DK. Walters, IP.Banke, P. Steinmann, GJ. Puskas, J.Bertz, K.Rentsch, F.Ehrensperger, W. Born, B. Fuchs. The Antineoplastic Antibiotic Taurolidine Promotes Lung and Liver Metastases in Two Syngeneic Osteosarcoma Mouse Models and Exhibits Severe Liver Toxicity.
    Int J Cancer 131(5):E804-12, 2012 doi: 10.1002/ijc.27378
  68. M.Betz, C.Dumont, B.Fuchs, GU.Exner. Epiphyseal Distraction for Joint Preservation in Malignant Metaphyseal Bone Tumors in Children.
    Clin Orthop Rel Res 470(6):1749-54, 2012
  69. K.Reidy, C.Campanile, R.Muff, W.Born, B.Fuchs. mTHPC-mediated Photodynamic Therapy is Effective in the Metastatic Human 143B Osteosarcoma Cells.
    Photochemistry and Photobiology 88(3):721-7, 2012
  70. M.Erschbamer, B.Bode, FM.Buck, B.Fuchs. A Rare Periosteal Diaphyseal Lesions of the Ulna.
    Open Orthop J 6:8-10, 2012
  71. K.Modaressi, F.Niggli, B.Fuchs. Strategisches Vorgehen bei Verdacht auf Knochensarkom.
    Schweizerische Zeitschrift für Onkologie SZO 2: 12-17, 2012
  72. K.Berndt, J.Vogel, C.Bühler, P.Vogt, W.Born, B.Fuchs. A New Method for Repetitive Drug Infusion into the Femoral Artery of Mice.
    J Am Assoc Lab Animal Science 51(6):825-31, 2012
  73. G.Studer, B.Bode, B.Fuchs. Extremitäten-Weichteilsarkom des Erwachsenen: Stellenwert der Radiotherapie
    Info @ Onkologie 02:14-17, 2012
  74. MJE.Arlt, W.Born, B.Fuchs. Taurolidine: Mode of Administration in Mouse Tumor Models
    Int J Cancer 131(5):E1053-4, 2012 doi:10.1002/ijc.27569
  75. K.Modaressi, B.Fuchs. Die Chirurgische Behandlung von Sarkomen
    Leading Opinions Hämatologie & Onkologie 2:74-76, 2012
  76. M.Arlt, W.Born, B.Fuchs. Improving Visualization of Lung Metastases by Combining X-Gal Staining of LacZ-tagged Tumor Cells with In-situ Perfusion and Fixation of the Lung Tissue
    J Vis Exp (66):e4162, 2012 DOI 10.3791/4162
  77. R.Muff, R.Kumar, S.Botter, W.Born, B.Fuchs: Genes Regulated in Metastatic Osteosarcoma: Evaluation by Microarray Analysis in Four Human and Two Mouse Cell Line Systems.
    Sarcoma 2012; 2012:937506 DOI 10.1155/2012/937506
  78. M.Glanzmann, B.Fuchs, H.Schwyzer. Chronische Ellbogenschmerzen einer Volleyballerin.
    Arthroskopie 1-4, 2012 DOI 10.1007/s00142-012-0711-2
  79. A.Gvozdenovic, MJE. Arlt, C.Campanile, P.Brennecke, K.Husmann, Y. Li, W.Born, R.Muff, B.Fuchs. CD44 Enhances Tumor Formation and Lung Metastasis in Experimental Osteosarcoma and is an Additional Predictor for Poor Patients’ Outcome.
    J Bone Min Res 28(4):838-47, 2013
  80. K.Husmann, MJE.Arlt, R.Muff, B.Langsam, J.Bertz, W.Born, B.Fuchs. Matrix Metalloproteinase 1 promotes Tumor Formation and Lung Metastasis in an Intratibial Injection Osteosarcoma Mouse Model.
    BBA Molecular Basis of Disease 1832(2):347-54, 2013
  81. T.Jentzsch, M.Erschbamer, F.Seeli, B.Fuchs. Extensor Function After Medial Gastrocnemius Flap Reconstruction of the Proximal Tibia.
    Clin Orthop Rel Res 471(7):2333-9, 2013
  82. C.Campanile, M.Arlt, A.Gvozdenovic, P.Brennecke, A.Sabile, M.Honer, C.Fischer, A.Mueller, S. Ametamey, S.Krämer, R.Schibli, W.Born, B.Fuchs. Characterization of Different Osteosarcoma Phenotypes by PET Imaging in Preclinical Animal Models
    J Nuclear Medicine 54(8):1362-8, 2013
  83. K.Modaressi, B.Fuchs, P.Bode, R.Sutter, M.Decurtins, U.Weber. Osteoblastoma of the Ilium mimicking sacroiliitis.
    Arthritis Rheum 65(6):1674, 2013
  84. A.Gozdenovic, MJE.Arlt, C.Campanile, P.Brennecke, K.Husmann, W.Born, R.Muff, B.Fuchs: Silencing of CD44 Gene Expression in Human 143-B Osteosarcoma Cells Promotes Metastasis of Intratibial Tumors in SCID Mice
    PLosOne 8(4):e60329, 2013
  85. K.Berndt, C.Campanile, R.Muff, E.Strehler, W.Born, B.Fuchs. Evaluation of Quercetin as a Potential Drug in Osteosarcoma Treatment.
    Anticancer Res 33(4):1297-306, 2013
  86. A.Sabile, M.Arlt, R.Muff, B.Bode, B.Langsam, J.Bertz, T.Jentzsch, W.Born, B.Fuchs: Caprin1 promotes Metastasis in an Experimental Animal Model of Osteosarcoma.
    BBA Molecular Basis of Disease 1832(8):1173-82, 2013
  87. S.Crivelli-Ochsner, B.Bode, Y.Nussbaumer-Ochsner, B.Fuchs. Giant Cell Angioblastoma in an Adult: A Unique Presentation.
    Rare Tumors 5e27:98-100, 2013
  88. K.Modaressi, G.Studer, B.Bode, S.Hofer, B.Fuchs. Knochenmetastasen – Abklärung und Therapie. Schlaglicht Schweizerische Aertzte Zeitung, Frühjahr 2013.
    Swiss Med Forum 13(2930):571-79, 2013
  89. K.Wieser, K.Modaressi, F.Seeli, B.Fuchs. Autologous Double-Barrel Vascularized Fibular Bone Graft for Arthrodesis of the Shoulder after Tumor Resection.
    Archives Orthop Traumatol 133(9):1219-24, 2013
  90. P.Brennecke, MA Arlt, R.Muff, C.Campanile, A.Gvozdenovic, K.Husmann, N.Holzwarth, E.Cameroni, F.Ehrensperger, M.Thelen, W.Born, B.Fuchs. Expression of the Chemokine Receptor CXCR7 in CXCR4-Expressing Human 143B Osteosarcoma Cells Enhances Lung Metastases of Intratibial Xenografts in SCID Mice.
    PLosOne  8(9):e74045, 2013
  91. MJE.Arlt, IJ.Banke, J.Bertz, R.Mohan, R.Muff, W.Born, B.Fuchs. Reduced Latency in the Metastatic Niche Contributes to the More Aggressive Phenotype of LM8 Compared to Dunn Osteosarcoma Cells.
    Sarcoma 2013; 2013:404962 doi: 10.1155/2013/404962
  92. D.Meier, C.Campanile, S, Botter, W.Born, B.Fuchs. Cytotoxic Efficacy of Photodynamic Therapy in osteosarcoma Cells in vitro.
    J Vis Exp 2014 Mar 18; (85). Doi:10.3791/51213
  93. P.Brennecke, M.Arlt, K.Husmann, C.Campanile, A.Gvozdenovic, T.D’Apuzzo, M.Thelen, W.Born, B.Fuchs. CXCR4 Antibody Treatment Suppresses Metastatic Spread to the Lung of Intratibial Human Osteosarcoma Xenografts In Mice.
    Clin Exp Metastasis 31(3):339-49, 2014
  94. C.Pauli, B.Fuchs, C.Pfirrmann, JA.Bridge, S.Hofer, B.Bode: Response of an Aggressive Periosteal Aneurysmal Bone Cyst (ABC) of the Radius to Denosumab Therapy.
    World J Surg Oncol 12(1): 17, 2014  Doi: 10.1186/1477-7819-12-17 (IF 1.092)
  95. K.Modaressi, P.Giovanoli, P.Schneider, T.Sulser, C.Werner, B.Bode, B.Fuchs. Rezidivierendes Rektumkarzinom: Sakrektomie mit kompletter dorsaler Exenteration.
    Leading Opinions Orthopedics & Rheumatology 1/14:46-8, 2014
  96. S.Botter, D.Neri, B.Fuchs. Recent Advances in Osteosarcoma.
    Curr Opin Pharmacol 16C:15-23, 2014
  97. NR.Datta, E.Puric, R.Schneider, B.Fuchs, S.Bodis, D.Weber. HYPROSAR: Hyperthermia and Proton Radiotherapy in Soft Tissue Sarcoma.
    Leading Opinions Hämatologie & Onkologie 2:158-60, 2014
  98. M.Arlt, I.Banke, D.Walters, K.Berndt, E.Strehler, W.Born, B.Fuchs. The Use of LacZ-transduced Tumor Cells Enhances the Sensitivity of Micrometastasis Detection: A Comparative Study of Gemcitabine Treatment Efficacy in the Mouse LM8 Osteosarcoma Cell Model.
    J Cancer Res Ther 2(6):89-95, 2014
  99. T.Jentzsch, B.Robl, M.Husmann, B.Bode, B.Fuchs. Worse Prognosis of Osteosarcoma Patients expressing IGF-1 on a Tissue Microarray
    Anticancer Res 34(8):3881-9, 2014
  100. RMR. Kumar, MM.Betz, B.Robl, W.Born, B.Fuchs. ΔNp63alpha Exerts Its Oncogenic Potential via Transcriptionally Regulating GLI2 in Osteosarcoma Cells.
    BMC Cancer 14: 559, 2014
  101. M.Rimann, S.Laternser, A.Gvozdenovic, R.Muff, B.Fuchs, J.Kelm, U.Graf-Hausner. An In-vitro Osteosarcoma 3D Microtissue Model for Drug Development.
    J Biotechnology 189C:129-135, 2014
  102. T.Jentzsch, B.Robl, M.Husmann, B.Bode, B.Fuchs. Expression of MSH2 and MSH6 on a Tissue Microarray in Patients with Osteosarcoma.
    Anticancer Res 34(12):6961-72, 2014
  103. B.Fuchs. Research and Development in Tumour Surgery: The Importance of Team Work.
    Swiss Cancer Research Foundation 1:95-99, 2014
  104. R.Cathomas, C.Rothermundt, B.Bode, B.Fuchs, R.von Moos, M.Schwitter. RANK ligand Blockade with Denosumab in Combination with Sorafenib in Chemorefractory Osteosarcoma: a possible Step forward?
    Oncology 88(4):257-60, 2015
  105. K.Husmann, M.Arlt, P.Jirkof, M.Arras, W.Born, B.Fuchs. Primary Tumour Growth in an Orthotopic Osteosarcoma Mouse Model Is Not Inflenced By Analgesic Treatment with Buprenorphine And Meloxicam.
    Laboratory Animals 49(4):284-93, 2015
  106. B.Robl, C.Pauli, S.Botter, B.Bode, B.Fuchs. Prognostic Value of Tumor Suppressors in Osteosarcoma Before and After Neoadjuvant Chemotherapy.
    BMC Cancer 15(1):379- , 2015
  107. NR.Datta, R.Grobholz, E.Puric, B.Bode, N.Lomax, S.Khan, US. Gaipl, B.Fuchs, S.Bodis. Enhanced Tumour Regression in a Patient of Liposarcoma Treated with Radiotherapy and Hyperthermia: Hint for Dynamic Immunomodulation by Hperthermia.
    Int J Hyperthermia 20:1-4, 2015
  108. A.Boro, M.Arlt, H.Lengnick, B.Robl, M.Husmann, J.Bertz, W.Born, B.Fuchs. Prognostic Value and in-vitro Biological Relevance of Neuropilin 1 and Neuropilin 2 in Osteosarcoma.
    Am J Translational Res 7(3):640-53, 2015
  109. T.Jentzsch, B.Fuchs. Therapie von Sarkomen.
    InFo@Onkologie&Hämatologie 3(5):1-6, 2015
  110. G.Studer, M.Brown, B.Fuchs. Radiotherapie bei Weichteilsarkomen des Erwachsenen: Präoperative und Dosis-Volumen-konformierende Anwendung
    InFo@Onkologie 2:13-15, 2015
  111. S.Hodel, F.Seeli, B.Fuchs. Demographische Analyse von Patienten mit Osteosarkom, Chondrosarkom, Ewing’s Sarkom von einem Sarkomzentrum in der Schweiz.
    PRAXIS Schweizerische Rundschau für Medizin 104(13):673-80, 2015
  112. R.Muff, P.Rath, R.Kumar, K.Husmann, W.Born, M.Baudis, B.Fuchs. Genomic Instability of Osteosarcoma Cell Lines during Long-term in vitro Culture.
    PlosOne 10(5):e0125611, 2015
  113. R.Kumar, B.Fuchs. Hedgehog Signaling Inhibitors as Anti-cancer Agents in Osteosarcoma.
    Cancers  7(2):784-94, 2015
  114. R.Kumar, M.Arlt, B.Robl, A.Kuzmanov, O.Neklyudova, K.Husmann, W.Born, B.Fuchs. Sunitinib Malate (SU-11248) Reduces Intratibial Tumour Burden And Lung Metastasis In a Preclinical Mouse Model Of Osteosarcoma.
    Am J Cancer Res 5(7):2156-68, 2015
  115. K.Husmann, P.Ducommun, A.Sabile, E.Pedersen, W.Born, B.Fuchs. Signal Transduction and Downregulation of C-Met in HGF-stimulated Low and Highly Metastatic Human Osteosarcoma Cell Lines.
    Biochem Biophys Res Commun 464(4):1222-7, 2015
  116. B.Fuchs. Swiss National Sarcoma Advisory Board: Vorstellung des Schweizer Konsensus.
    Leading Opinions Hämatologie&Onkologie 3(15):78-80, 2015
  117. D.Müller, B.Fuchs. Whoops Läsionen bei Weichteilsarkomen.
    InFo@Onkologie&Hämatologie 8:26-29, 2015
  118. M.Ture, J.Barth, F.Angst, A.Aeschlimann, U.Schnyder, N.Zerkiebel, J.Perseus, C.Renner, P.Imesch, B.Fuchs, G.Huber, H.Walt, C.Martin-Soelch, J.Jenewein. Use of Inpatient Rehabilitation for Cancer patients in Switzerland: Who undergoes Cancer Rehabilitation?
    Swiss Medical Weekly December 4, 2015 DOI 10.4414/smw.2015.14214
  119. A.Boro, D.Bauer, W.Born, B.Fuchs. Plasma Levels of MIRNA-155 as a Powerful Diagnostic Marker for Dedifferentiated Liposarcoma.
    Am J Cancer Res 6(2):544-52, 2016
  120. R.Muff, S.Botter, K.Husmann, J.Tchinda, P.Selvam, F.Seeli-Maduz, B.Fuchs. Explant Culture of Sarcoma Patients’ Tissue.
    Lab Invest  DOI:10.1038 April 26, 2016 (IF 3.8)
    doi: 10.1038/labinvest.2016.49. Epub 2016 Apr 25 / PMID: 27111283
  121. O.Neklyudova, M.Arlt, P.Brennecke, M.Thelen, A.Gvozdenovic, A.Kuzmanov, B.Robl, S.Botter, W.Born, B.Fuchs. Altered CXCL12 Expression Reveals a Dual Role of CXCR4 in Osteosarcoma Primary Tumor Growth and Metastasis.
    J Cancer Res Clin Oncol Epub ahead of print June 14 2016 (IF 3.141)
    doi: 10.1007/s00432-016-2185-5. Epub 2016 Jun 14 / PMID: 27300512
  122. Daniel Burger, M.Pumberger, B.Fuchs. An Uncemented Spreading Stem for the Fixation in the Metaphyseal Femur: A Preliminary Report
    Sarcoma May 15, 2016:7132838. Doi:10.1155/2016/7132838 (IF XY)
    doi: 10.1155/2016/7132838. Epub 2016 May 15 /  PMID: 27293377
  123. R.Kumar, A.Boro, B.Fuchs. Involvement and Clinical Apsects of microRNA in Osteosarcoma: A Review.
    Int J Mol Sci 2016 Jun 3:17(6) (IF 3.257)
    doi: 10.3390/ijms17060877 / PMID: 27271607
  124. A. Gvozdenovic, A.Boro, D.Meier, B.Bode-Lesniewska, W.Born, R.Muff, B.Fuchs. Targeting αvβ3 and αvβ5 Integrins Inhibits Pulmonary Metastasis in an Intratibial Xenograft Osteosarcoma Model.
    Oncotarget 7(34):55141-55154, 2016 (IF 6.359)
    doi: 10.18632/oncotarget.10461 / PMID: 27409827
  125. B.Robl, S.Botter, G.Pellegrini, O.Neklyudova, B.Fuchs. Evaluation of Intraarterial and Intravenous Cisplatin Chemotherapy in the Treatment of Metastatic Osteosarcoma using an Orthotopic Xenograft Mouse Model.
    J Exp Clin Cancer Res 35(1):113, 2016 (IF 4.357)
    doi: 10.1186/s13046-016-0392-1 / PMID: 27421768
  126. T.Jentzsch, L.Vlachopoulos, P.Fürnstahl, D.Müller, B.Fuchs. Tumor Resection at the Pelvis using Three-dimensional Planning and Patient-specific Instruments: A Case Series.
    World Journal of Surg Oncology 14(1):249, 2016 (IF 1.458)
    doi: 10.1186/s12957-016-1006-2 / PMID: 27729037
  127. M.Scaglioni, N.Lindenblatt, A.Barth, B.Fuchs, W.Weder, P.Giovanoli. Free Fillet Flap Application to Cover Forequarter or Traumatic Aputation on an Upper Extremity: A Case Report.
    Microsurgery 36(8):700-704, 2016
    doi: 10.1002/micr.30124. Epub 2016 Oct 20 / PMID: 27762441
  128. A.Arteau, B.Fuchs. Complete Deltoid Resection in Infancy results in Normal Shoulder Function at Longterm Followup.
    J Medical Case Reports 11(1):13, 2017 (IF 0.4)
    doi: 10.1186/s13256-016-1132-z.PMID: 28086945
  129. D.Meier, S.Botter, C.Campanile, B.Robl, S.Gräfe, G.Pellegrini, W.Born, B.Fuchs. Foscan and Foslip based Photodynamic Therapy in Osteosarcoma in vitro and in Intratibial Mouse Models.
    International J Cancer Dec 10 2016 doi:10.1002/jc.30572 (IF 5.531)
    doi: 10.1002/ijc.30572 / PMID: 27943293
  130. B.Robl, SM.Botter, A.Boro, D.Meier, D.Neri, B.Fuchs. Evaluation of F8-TNF-alpha in Models of Early and Progressive Metasttic Osteosarocma.
    Transl Oncol. 10(3):419-430, 2017
    doi: 10.1016/j.tranon.2017.02.005. Epub 2017 Apr 25 / PMID: 28448958
  131. A.Gvozdenovic, A. Boro, W.Born, R.Muff, B.Fuchs: A Bispecific Antibody Targeting IGF-IR and EGFR has tumor and metastasis suppressive activity in an orthotopic xenograft osteosarcoma mouse model.
    Am J Cancer Res 7(7):1435-1449, 2017
    eCollection 2017 / PMID: 28744395
  132. B.Fuchs. CORR Insights: Micrometastatic Drug Screening Platform Shows Heterogenous Response to MAP Chemotherapy in Osteosarcoma Cell Lines.
    Clin Orthop Rel Res 476(7):1412-1414, 2018
    doi: 10.1097/01.blo.0000540061.16243.f9 / PMID: 29889114
  133. JCF.Wilburger, C.Kettelhack, B.Fuchs, DJ.Schaefer, R.Osinga. Giant Myxoid Liposarcoma of the Gluteal Region: Case Report of Patient Caused Delay of Surgical Treatment ad Review of the Literature.
    J Surg Case Rep. doi:10.1093, Oct 08, 2018
    doi: 10.1093/jscr/rjy265. eCollection 2018 Oct / PMID: 30310650
  134. G.Studer, C.Glanzmann, F.Maduz, B.Bode, B.Fuchs. Preoperative IMRT for Soft-tissue Sarcoma of the Extremities and Trunk: Low Rate of Wound Complications.
    Current Orthopaedic Practice 29(5):466-470, 2018
  135. B.Fuchs, A.Krieg, C.Kettelhack, G.Studer, B.Bode, and the SwissSarcomaNetwork. Behandlung von Primären Knochentumoren am Becken.
    InFo Onkologie Hämatologie 8-12, 2018 (Medizinonline.ch)
  136. B.Fuchs, A.Krieg, C.Kettelhack, B.Bode, G.Studer, and the SwissSarcomaNetwork. Sakropelvine Osteotomie für die Typ-I-Resektion von Knochentumoren am Becken.
    Leading Opinions Orthopädie & Rheumatologe 4:70-73, 2018
  137. MJ.Arlt, A.Kuzmanov, J.Snedeker, B.Fuchs, U.Silvan, A.Sabile. Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome.
    BMC Cancer 19(1):83, 2019
    doi: 10.1186/s12885-019-5303-3 / PMID: 30654764
  138. Beata Bode-Lesniewska, Christine Fritz, Gerhard U. Exner, Ulrich Wagner, Bruno Fuchs. EWSR1-NFATC2 and FUS-NFATC2 gene fusion associated mesenchymal tumors – clinicopathologic correlation and literature review.
    Sarcoma 2019;2019:9386390
    doi: 10.1155/2019/9386390. eCollection 2019 / PMID: 31049020
  139. A.Najafi, B.Fuchs, CA.Binkert: Mid-term results of MR-guided high-intensity focused ultrasound treatment for relapsing superficial desmoids.
    Int J Hyperthermia 36(1):538-542, 2019
  140. Studer G, Hofer S, Treumann T, Schweiwiller A, Bode-Lesniewska B, Diebold J, Fuchs B. Information zum überregionalen Schweizerischen Sarkom-Netzwerk (SSN).
    Luzerner Arzt 2019 (118): 56-59
  141. Studer G, Treumann T, Hofer S, Bode B, Fuchs B. Work-up und präoperative Radiotherapie bei Weichteilsarkomen des Erwachsenen.
    Schweizer Krebsbulletin, Band 39, Juni 2019, Seiten 121-124
  142. Fuchs B. Qualitätssicherung in der Behandlung von Sarkomen: Eine interdisziplinäre und interinstitutionelle Herausforderung. Editorial.
    Schweizer Krebsbulletin, Band 39, Juni 2019, Seiten 99-101
  143. Krieg AH, Wirth C, Lenze U, Kettelhack C, Coslovsky M, Baumhoer D, Klenke F, Siebenrock K, Exner GU, Bode-Lesniewska B, Fuchs B, Cherix S, Hefti F. Extra-abdominal desmoid tumours – further evidence for the watchful waiting policy.
    Swiss Medical Weekly 2019 Jul 24; 149: w20107. Doi: 10.4414/smw.2019.20107.
    doi: 10.4414/smw.2019.20107. eCollection 2019 Jul 15 / PMID: 31340054
  144. B.Fuchs, G.Studer, B.Bode, S.Breitenstein. Swiss Sarcoma Network (SSN).
    Swiss Knife 3:10-12, 2019
  145. J. Urdinez, A.Mazumdar, MJ.Arlt, R.Muff, S.Botter, B.Bode-Lesniewska, B.Fuchs, J.Snedeker, A.Gvozdenovic. The miR-143/145 Cluster, a Novel Diagnostic Biomarker in Chondrosarcoma, acts as a Tumor Suppressor and directly inhibits Fascin-1.
    J Bone Miner Res 2020 35(6):1077-1091, 2020
    doi: 10.1002/jbmr.3976. Epub 2020 Mar 10 / PMID: 32027760
  146. A.Mazumdar, J.Urdinez, A.Boro, J.Migliavacca, MJ.Arlt, B.Fuchs, J.Snedeker, A.Gvozdenovic. Osteosarcoma-derived extracellular Vesicles induce Lung Fibroblast Reprograming.
    Int J Mol Sci 2020, 21(15):5451 DOI: 10.3390/ijms21155451.PMID:32751693
    doi: 10.3390/ijms21155451 / PMID: 32751693
  147. M.Scaglioni, M.Meroni, E.Fritsche, B.Fuchs: Reply to: Real-time lymph flow projection mapping using near-infrared fluorescence.
    J Surg Oncol 2020 Dec 17.
    doi:10.1002/jso.26331
  148. B.Fuchs. B.Bode, G.Studer, S.Breitenstein. Wie entwickelt sich die Sarkomchirurgie?
    Leading Opinions Hämatologie & Onkologie. 8:43-45, 2020
  149. Alekhya Mazumdar, Joaquin Urdinez, Aleksandar Boro, Matthias J.E. Arlt, Fabian E. Egli, Barbara Niederöst, Patrick K. Jaeger, Greta Moschini, Roman Muff, Bruno Fuchs, Jess G. Snedeker and Ana Gvozdenovic. Exploring the Role of Osteosarcoma-derived Extracellular Vesicles in Pre-metastatic Niche Formation and Metastasis in the 143-B Xenograft Mouse Osteosarcoma Model.
    Cancers Nov 20; 12(11):3457, 2020.
    doi 10.3390/cancers 12113457
  150. M.Scaglioni, M.Meroni, E.Fritsche, B.Fuchs: Reply to: Lymph interpositional flap transfer for upper thigh soft tissue and lymphatic reconstruction without lymphovenous anastomosis.
    J Surg Oncol 2021 Feb; 123(2):700.
    doi:10.1002/jso.26293
  151. SwissSarcomaNetwork (SSN) – Fakten und erste Zahlen zur Verbesserung der Qualität in der Behandlung von Patienten mit Sarkomen.
    Luzerner Arzt 124:61-64, 2021
  152. Meier, Daniela; Lodberg, Andreas; Gvozdenovic, Ana; Pellegrini, Giovanni ; Neklyudova, Olga ; Born , Walter ; Fuchs, Bruno ; Eijken, Marco; Botter, Sander M.: „Inhibition of the Activin Receptor Signaling Pathway: A Novel Intervention against Osteosarcoma“
    Cancer Med 10:286-296, 2021
    doi: 10.1002/cam4.3581. Epub 2020 Nov 12 / PMID: 33179858
  153. MF.Scaglioni, M.Meroni, E.Fritsche, B.Fuchs. Combined pedicled superficial circumflex iliac artery perforator (SCIP) flap with lymphatic tissue preservation and lymphovenous anastomosis (LVA) for defect reconstruction and lymphedema-lymphocele prevention in thigh sarcoma surgery: Preliminary results.
    J Surg Oncology 123(1):96-103, 2021
    doi: 10.1002/jso.26228. Epub 2020 Sep 22 / PMID: 32964444
  154. Scaglioni MF, Meroni M, Fritsche E, Fuchs B. Reply to: Real-time lymph flow projection mapping using near infrared fluorescence.
    J Surg Oncol 123(2):703, 2021
  155. Scaglioni MF, Meroni M, Fritsche E, Fuchs B. Reply to: Lymph interpositional flap transfer for upper thigh soft tissue and lymphatic reconstruction without lymphovenous anastomosis.
    J Surg Oncology 123(2): 700, 2021
  156. B.Fuchs. B.Bode, G.Studer, S.Breitenstein. Wie entwickelt sich die Sarkomchirurgie?
    Leading Opinions Orthopädie & Traumatologie. 1:16-18, 2021
  157. M.Scaglioni, E.Fritsche, B.Fuchs, M.Meroni. The use of pedicled chimeric superficial curcumflex iliac artery perforator (SCIP) flap as interpositional flap for deep thigh defect reconstruction: a case report.
    Microsurgery 2021 Oct 09.
    doi: 10.1002/micr.30823. Epub 2021 Oct 9 / PMID: 34626139
  158. M.Greminger, B.Bode, B.Fuchs: Extra-axial chordoma within a tendon of the hand.
    J Hand Surg Eur Vol.: 2021 Nov 24:17531934211059872
    doi: 10.1177/17531934211059872. Epub 2021 Nov 24 / PMID: 34816758
  159. B.Fuchs, G.Studer, B.Bode, H.Wellauer, A.Frei, C.Theus, G.Schüpfer, J.Plock, H.Windegger, S.Breitenstein. Development of a value-based health care delivery (VBHC) model for sarcoma patients.
    Swiss Medical Weekly 2021 Dec 24; 151:w30047
    doi: 10.4414/smw.2021.w30047. eCollection 2021 Dec 20 / PMID: 34964578
  160. Scaglioni MF, Meroni M, Fritsche, E, Fuchs B.: Total Groin Defect Reconstruction by Lymphatic Flow-Through (LyFT) pedicled deep inferior epigastric artery perforator (DIEP) Flap resorting to its superficial veins for lymphovenous anastomosis (LVA): a case report.
    Microsurgery 42(2): 170-175, 2022
    doi: 10.1002/micr.30712. Epub 2021 Jan 23 / PMID: 33484183
  161. Scaglioni MF, Meroni M, Fritsche, E, Fuchs B: Combined double superficial iliac artery perforator flap with lymphatic tissue preservation and lymphovenous anastomosis for lymphatic sequelae prevention in thigh defect reconstruction: a case report.
    Microsurgery 42(3):265-270, 2022 doi 10.1002/micr.30723
  162. MF.Scaglioni, M.Meroni, B.Fuchs, E.Fritsche: Lymphatic complications prevention and soft tissue reconstruction after soft tissue sarcoma resection in the limbs.
    Medicina 2022 Jan 2; 58(1)_67.
    doi: 10.3390/medicina58010067 / PMID: 35056375
  163. B.Fuchs, P.Heesen: Real-time interaktive Analyse der Behandlungsqualität von Sarkom-Patienten.
    Info@onco-suisse 2022 (1):13-20
  164. A.Frei, P.Heesen, M.Scaglioni, P.Giovanoli, S.Breitenstein, B.Fuchs: Definition of the Surgical Case Complexity of Soft Tissue Tumors of the Extremities and Trunk.
    Cancers 14(6): 1559, 2022
    doi: 10.3390/cancers14061559 / PMID: 35326712
  165. N.Mosku, P.Heesen, G.Studer, B.Bode, N.Klaas, L.Kern, MF.Scaglioni, B.Fuchs: Biopsy Ratio of suspected to Confirmed Sarcoma Diagnosis.
    Cancers 14(7): 1632, 2022
    doi: 10.3390/cancers14071632. / PMID: 35406402
  166. P.Häfeli, P.Möhl, B.Fuchs, G.Studer, S.Aebi, R.Lopez Benitez, B.Link: Die interdisziplinäre Behandlung von Knochenmetastasen am LUKS: Teil 1 – Die erweiterte kombinierte chirurgisch-interventionelle Therapie: Embolisation, Biopsie, Ablation und operative Versorgung in einer Sitzung.
    Luzerner Arzt accepted March 2022
  167. G.Studer, B.Bode, M.Scaglioni, P.Heesen, C.Theus-Steinmann, C.Glanzmann, B.Fuchs: Schweizerisches Sarkom-Netzwerk – Aktivitäten und erste Resultate.
    Luzerner Arzt 129:57-61, 2022
  168. M.Scaglioni, M.Meroni, B.Fuchs, M.Knobe, E.Fritsche: The use of the Chimeric Conjoint Flap Technique for Complex Defects Reconstruction throughout the Body: Clinical experience with 28 cases.
    Microsurgery July 01; 2022. DOI:10.1002/micr.30936. PMID: 35775973
  169. H.Wellauer, G.Studer, B.Bode-Lesniewska, B.Fuchs. Time and Accuracy to establish the diagnosis of soft tissue tumors: A comparative analysis from the SwissSarcomaNetwork.
    Sarcoma 2022 April 30; 2022:7949549
    doi: 10.1155/2022/7949549. eCollection 2022.PMID: 35535046
  170. R. van Leeuwen, M.Beck, B.Fuchs. Internal hemipelvectomy through a periacetabular osteotomy combined with an extraarticular (proximal) femur resection using a single approach: a series of cases.
    J Surg Res 5(2):305-321, 2022
    doi: 10.26502/jsr.10020224
  171. C.Fritz, M.Meroni, J.Tartanus, B.Fuchs, M.Scaglioni: Pedicled double-paddle posteriomedial thigh (vPMT) flap for double-layer closure and reconstruction of upper thigh defect after sarcoma resection: A case report.
    Microsurgery Aug 10 2022
    doi:10.1002/micr.30948. PMID: 35946575
  172. MF.Scaglioni, M.Meroni, E.Fritsche, B.Fuchs. Lymphatic complications prevention and soft tissue reconstruction after soft tissue sarcoma resection in the limbs.
    Medicina 2022; 58(67):1-8
    doi: 10.3390/medicina58010067; PMID: 35056375