Anästhesiologie

Prof. Dr. med. Michael Ganter

Direktor und Chefarzt Institut für Anästhesiologie
Facharzt für Anästhesiologie und Intensivmedizin
Fähigkeitsausweis Notarzt SGNOR

Medizinische und akademische Laufbahn
1997Staatsexamen, Universität Zürich
1998Dissertation und Promotion, Universität Zürich
2005Amerikanisches Staatsexamen (ECFMG)
2008Habilitation (Venia legendi), Universität Zürich
2015Professur (Titularprofessor), Universität Zürich
Facharzt- und Fähigkeitsausweise
2002Europäisches Diplom in Anästhesiologie und Intensivmedizin (EDAIC)
2002Fähigkeitsausweis Notarzt SGNOR
2003Facharzt für Anästhesiologie
2004Facharzt für Intensivmedizin
Zusatzqualifikationen und Aktivitäten
seit 2008Lehrbeauftragter, Medizinische Fakultät der Universität Zürich
2009Good Clinical Practice (GCP) Module 1-3, Universität Zürich
seit 2009Dozent, Höhere Fachschule für Intensiv-, Notfall- und Anästhesiepflege Zürich (Z-INA)
2010-11St. Galler Management-Seminar für Führungspersonen im Gesundheitswesen, Universität St. Gallen (IDT-HSG)
seit 2014
Vorstandsmitglied, Schweizerische Gesellschaft für Anästhesiologie und Reanimation (SGAR), Ressort Qualitätsmanagement
2015Tutor, fokussierte Sonographie ICAN Anästhesie
Weiterbildung zum Facharzt
1998Anästhesiologie, UniversitätsSpital Zürich
1998-1999Innere Medizin und REGA, Kantonsspital Glarus
1999-2002Anästhesiologie und Intensivmedizin, Stadtspital Triemli Zürich
2002-2003Anästhesiologie und Intensivmedizin, UniversitätsSpital Zürich
Tätigkeit als Facharzt
2003-2004Oberarzt chirurgische Intensivmedizin, UniversitätsSpital Zürich
2004-2007Assistant Professor, Department of Anesthesia and Perioperative Care, University of California San Francisco, USA
2007-2011Oberarzt Anästhesiologie, UniversitätsSpital Zürich
2011-2012Leitender Arzt Anästhesiologie, UniversitätsSpital Zürich
seit 2012Direktor und Chefarzt, Institut für Anästhesiologie und Schmerztherapie, Kantonsspital Winterthur
Spezialinteressen
  • Anästhesie in der Thorax- und Viszeralchirurgie
  • Regionalanästhesie
  • Transfusionsmedizin, Hämostaseologie und Patient Blood Management
  • Molekularbiologische Mechanismen im akuten Lungenschaden
Mitgliedschaften

  • Schweizerische Ärztegesellschaft (FMH)
  • Schweizerische Gesellschaft für Anästhesiologie und Reanimation (SGAR)
  • Schweizerische Gesellschaft für Notfall- und Rettungsmedizin (SGNOR)
  • Schweizerische Gesellschaft für Ultraschall in der Medizin (SGUM / ICAN)
  • Gesellschaft der Zürcher Anästhesieärzte (GZA)
  • European Society of Anaesthesiologists (ESA)
  • American Society of Anesthesiologists (ASA)
  • Trauma Anesthesia Society (TAS)
  • International Anesthesia Research Society (IARS)

Originalartikel

  1. Hofer CK, GANTER M, Tucci M, Klaghofer R, Zollinger A. How reliable is length-based determination of body weight and tracheal tube size in the paediatric age group? The Broselow tape reconsidered. Br J Anaesth 2002; 88: 283-5.
  2. Hofer CK, GANTER MT, Furrer L, Guthauser G, Klaghofer R, Zollinger A. Patients‘ needs and expectations regarding anaesthesia. A survey on the pre-anaesthetic visit of patients and anaesthesiologists. Anaesthesist 2004; 53: 1061-8.
  3. GANTER MT, Hofer CK, Zollinger A, Spahr T, Pasch T, Zalunardo MP. Accuracy and performance of a modified continuous intravascular blood gas monitoring device during thoracoscopic surgery. J Cardiothorac Vasc Anesth 2004; 18: 587-91.
  4. Vuichard D, GANTER MT, Schimmer RC, Suter D, Booy C, Reyes L, Pasch T, Beck-Schimmer B. Hypoxia aggravates lipopolysaccharid-induced lung injury. Clin Exp Immunol 2005; 141: 248-60.
  5. GANTER MT, Dalbert S, Graves D, Klaghofer R, Zollinger A, Hofer CK. Monitoring activated clotting time for combined heparin and aprotinin application: in vitro evaluation of a new aprotinin-insensitive test using SONOCLOT. Anesth Analg 2005; 101: 308-14.
  6. GANTER MT, Hofer CK, Spahn DR, Bruggisser M, Bombeli T, Seifert B, Pasch T, Zalunardo MP. The effect of clonidine on perioperative blood coagulation. J Clin Anesthesia 2005; 17: 456-62.
  7. Furrer L, GANTER MT, Klaghofer R, Zollinger A, Hofer CK. Preoperative fasting times. Patients‘ perspective. Anaesthesist 2006; 55: 643-9.
  8. Dalbert S, GANTER MT, Furrer L, Klaghofer R, Zollinger A, Hofer CK. Effects of heparin, haemodilution and aprotinin on kaolin-based activated clotting time: in vitro comparison of two different point of care devices. Acta Anaesthesiol Scand 2006; 50: 461-8.
  9. Hofer CK, GANTER MT, Matter-Ensner S, Furrer L, Klaghofer R, Genoni M, Zollinger A. Volumetric assessment of left heart preload by thermodilution: comparing the PiCCO-VoLEF system with transoesophageal echocardiography. Anaesthesia 2006; 61: 316-21.
  10. GANTER MT, Ware LB, Howard MB, Roux J, Gartland B, Matthay MA, Fleshner M, Pittet JF. Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury. Am J Physiol Lung Cell Mol Physiol 2006; 291:L354-61. 2
  11. Tucci MA*, GANTER MT*, Hamiel CR, Klaghofer R, Zollinger A, Hofer CK. Platelet function monitoring by the Sonoclot analyzer following in vitro tirofiban and heparin administration. J Thorac Cardiovasc Surg 2006; 131: 1314-22. *Authors contributed equally to this work
  12. GANTER MT, Monn A, Tavakoli R, Genoni M, Klaghofer R, Furrer L, Honegger H, Hofer CK. Monitoring activated clotting time for combined heparin and aprotinin application: in vivo evaluation of a new aprotinin-insensitive test using Sonoclot. Eur J Cardiothorac Surg 2006; 30: 278-84.
  13. Brohi K, Cohen MJ, GANTER MT, Matthay MA, Mackersie RC, Pittet JF. Acute traumatic coagulopathy: initiated by hypoperfusion, modulated through the protein C pathway? Ann Surg 2007; 245: 812-8.
  14. GANTER MT, Brohi K, Cohen MJ, Shaffer LA, Walsh MC, Stahl GL, Pittet JF. Role of the alternative pathway in the early complement activation following major trauma. Shock 2007; 28: 29-34.
  15. GANTER MT, Monn A, Tavakoli R, Klaghofer R, Zollinger A, Hofer CK. Kaolin-based activated clotting time measured by Sonoclot in patients undergoing cardiopulmonary bypass. J Cardiothorac Vasc Anesth 2007; 21: 524-8.
  16. Meyer S, Z’graggen BR, Blumenthal S, Borgeat A, GANTER MT, Reyes L, Booy C, Neff TA, Spahn DR, Beck-Schimmer B. Hypoxia attenuates effector-target cell interaction in the airway and pulmonary vascular compartment. Clin Exp Immunol 2007; 150: 358-67.
  17. Cohen MJ, Brohi K, GANTER MT, Manley GT, Mackersie RC, Pittet JF. Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway. J Trauma 2007; 63: 1254-62.
  18. GANTER MT, Schneider U, Heinzelmann M, Zaugg M, Lucchinetti E, Zollinger A, Hofer CK. How often should we perform arterial blood gas analysis during thoracoscopic surgery? J Clin Anesthesia 2007; 19: 569-75.
  19. GANTER MT, Cohen MJ, Brohi K, Chesebro BB, Staudenmayer KL, Rahn P, Christiaans SC, Bir ND, Pittet JF. Angiopoietin-2, marker and mediator of endothelial activation with prognostic significance early after trauma? Ann Surg 2008; 247: 320-6
  20. GANTER MT, Roux J, Miyazawa B, Howard M, Frank JA, Su G, Sheppard D, Violette SM, Weinreb PH, Horan GS, Matthay MA, Pittet JF. Interleukin-1ß causes acute lung injury via avb5 and avb6 integrin-dependent mechanisms. Circ Res 2008; 102: 804-12. 3
  21. Hofer CK, GANTER MT, Rist A, Matter-Ensner S, Klaghofer R, Genoni M., Zollinger A. Accuracy of preload assessment by different transesophageal echocardiographic techniques in patients undergoing cardiac surgery. J Cardiothorac Vasc Anesth 2008; 22: 236-42.
  22. Brohi K, Cohen MJ, GANTER MT, Schultz MJ, Levi M, Mackersie RC, Pittet JF. Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation & hyperfibrinolysis. J Trauma 2008; 64:1211-7.
  23. GANTER MT, Schmuck S, Hamiel CR, Wischmeyer PE, Heule D, Zollinger A, Hofer CK. Monitoring recombinant factor VIIa treatment: efficacy depends on high levels of fibrinogen in a model of severe dilutional coagulopathy. J Cardiothorac Vasc Anesth 2008; 22:675-80.
  24. GANTER MT, Roux J, Su G, Lynch SV, Deutschman CS, Weiss YG, Christiaans SC, Myazawa B, Kipnis E, Wiener-Kronish JP, Howard M, Pittet JF. Role of small GPTases and avb5 integrin in P. aeruginosa-induced increase in lung permeability. Am J Respir Cell Mol Biol 2009; 40: 108-18.
  25. Roux J, Carles M, Koh H, Goolaerts A, GANTER MT, Chesebro BB, Howard M, Houseman BT, Finkbeiner W, Shokat KM, Paquet AC, Matthay MA, Pittet JF. TGF-{beta}1 inhibits CFTRdependent cAMP-stimulated alveolar epithelial fluid transport via a PI3K-dependent mechanism. J Biol Chem 2010; 285: 4278-90.
  26. Goolaerts A, Roux J, GANTER MT, Shlyonsky V, Chraibi A, Stéphane R, Mies F, Matthay MA, Naeije R, Sariban-Sohraby S, Howard M, Pittet JF. Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel ENaC. Am J Respir Cell Mol Biol 2010; 43: 99-108.
  27. Beck-Schimmer B, Breitenstein S, Bonvini JM, Lesurtel M, GANTER M, Weber A, Puhan MA, Clavien PA. Protection of pharmacological postconditioning in liver surgery: results of prospective randomized controlled trial. Ann Surg 2012; 256:837-45.
  28. Kajdi ME, Beck-Schimmer B, Held U, Kofmehl R, Lehmann K, GANTER MT. Anaesthesia in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy: Retrospective analysis of a single centre three-year experience. World J Surg Oncol 2014; 12 (136): 1-9.
  29. GANTER MT, Blumenthal S, Dübendorfer S, Brunnschweiler S, Hofer T, Klaghofer R, Zollinger A, Hofer CK. The length of stay in the post-anaesthesia care unit correlates with pain intensity, nausea and vomiting on arrival. Perioper Med (Lond) 2014; 3 (10): 1-9.
  30. Beck-Schimmer B, Bonvini JM, Schadde E, Dutkowski P, Oberkofler CE, Lesurtel M, DeOliveira ML, Figueira ERR, Filho JAR, Auler Jr JOC, D’Albuquerque LAC, Reyntjens K, Wouters P, Rogiers X, Debaerdemaeker L, GANTER MT, Weber A, Puhan MA, Clavien PA, Breitenstein S. Conditioning with Sevoflurane in liver transplantation. Results of a multicenter randomized controlled trial. Transplantation 2015; 99:1606-12.
  31. Bischof DB*, GANTER MT*, Shore-Lesserson L, Hartnack S, Klaghofer R, Graves K, Genoni M, Hofer CK. Sonoclot’s viscoelastic blood coagulation measurement predicts postoperative bleeding in cardiac surgery after heparin reversal. J Cardiothorac Vasc Anesth 2015; 29:715-22. *Authors contributed equally to this work
  32. Neumayr A, Gnirke A, Schaeuble JC, GANTER MT, Sparr H, Zoll A, Schinnerl A, Nuebling M, Heidegger T, Baubin M. Patient satisfaction in out-of-hospital emergency care: a multicentre survey. Eur J Emerg Med 2015; Epub ahead of print Mar 19 (accepted 12.02.15).
  33. GANTER MT, Alhashemi JA, Al-Shabasy AM, Schmid UM, Schott P, Shalabi SA, Badri AM, Hartnack S, Hofer CK. Continuous cardiac output measurement by un-calibrated pulse wave analysis and pulmonary artery catheter in patients with septic shock. J Clin Monit Comp 2015: Epub ahead of print Feb 27 (accepted 23.02.15).

Fallberichte

  1. GANTER MT, Ganter CC, Schneemann M, Maggiorini M. Near-fatal tension pneumoperitoneum. Intensivmed 2004; 41: 352-7.
  2. Brenni M, Worn M, Bruesch M, Spahn DR, GANTER MT. Successful ROTEM-guided treatment of traumatic haemorrhage and coagulopathy due to hyperfibrinolysis using antifibrinolytic medication and fibrinogen concentrate. Acta Anaesthesiol Scand 2010; 54: 111-7. 4
  3. Inci I, Benden C, Kestenholz P, Hillinger S, Schneiter D, GANTER M, Bechir M, Grünenfelder J, Weder W. Simultaneous bilateral lobar lung transplantation: one donor serves two recipients. Ann Thorac Surg 2013; 96:e69-71.
  4. Buergi A, Jung B, Padevit C, John H, GANTER MT. Severe anaphylaxis – the secret ingredient. Anesth Analg Case Reports 2014; 2: 34-6.

Letters to the Editor

  1. Hofer CK, GANTER MT, Zollinger A. Evaluation of a modified ThermoWrap for the Allon warming system in patients undergoing elective off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2006; 131: 929-30.
  2. Tang JF, Pittet JF, GANTER MT. Bring rapidly degradable hydroxyethyl starch to the United States. Anesthesiology 2006; 104: 1105-6.
  3. Hofer CK, GANTER MT. Coagulation monitoring. Anesth Analg. 2008; 107: 2093- 4.
  4. Schaeuble JC, GANTER MT. Clarifying the indications for difficult airway alert forms. Anaesthesia. 2015; 70: 505-6.

Editorials

  1. GANTER MT, Pittet JF. Bombesin-like peptides: modulators of inflammation in acute lung injury. AJRCCM 2006; 173: 1-2.
  2. GANTER MT, Spahn DR. Preface on perioperative coagulation management. Best Pract Res Clin Anaesthesiol 2010; 24: vii-viii.
  3. Spahn DR, GANTER MT. Towards early individual goal-directed coagulation management in trauma patients. Br J Anaesth 2010; 105: 103-5.
  4. GANTER MT, Spahn DR. Active, personalized and balanced coagulation management saves lives in massive bleeding patients. Anesthesiology 2010; 113:1016-8.

Übersichtsarbeiten

  1. GANTER M, Zollinger A. Continuous intravascular blood gas monitoring: development, current technique and clinical use of a commercial device. Br J Anaesth 2003; 91: 397-407.
  2. GANTER MT, Hofer CK, Zollinger A. Current status of continuous intravascular blood gas monitoring. Int J Intens Care 2004; autumn: 94-102. 5
  3. Hofer CK, GANTER MT, Zollinger A. What technique should I use to measure cardiac output? Curr Opin Crit Care 2007; 13: 308-17.
  4. GANTER MT, Hofer CK. Current techniques and clinical use of viscoelastic point of care coagulation devices. Anesth Analg 2008; 106: 1366-75.
  5. Theusinger OM, Spahn DR, GANTER MT. Transfusion in trauma: why and how should we change our current practice? Curr Opin Anaesthesiol 2009; 22:305-12.
  6. Bischof D, Dalbert D, Zollinger A, GANTER MT, Hofer CK. Thrombelastography in the surgical patient. Minerva Anestesiol 2010; 76: 131-7.
  7. GANTER MT, Pittet JF. New insights into the acute coagulopathy in trauma patients. Best Pract Res Clin Anaesthesiol 2010; 24: 15-25.
  8. Hofer CK, Zollinger A, GANTER MT. Perioperative assessment of platelet function in patients under antiplatelet therapy. Expert Rev Med Devices 2010; 7: 625-37.
  9. Levi M, Fries D, Gombotz H, van der Linden P, Nascimento B, Callum JL, Bélisle S, Rizoli S, Hardy JF, Johansson PI, Samama CM, Grottke O, Rossaint R, Henny CP, Goslings JC, Theusinger OM, Spahn DR, GANTER MT, Hess JR, Dutton RP, Scalea TM, Levy JH, Spinella PC, Panzer S, Reesink HW. Prevention and treatment of coagulopathy in patients receiving massive transfusions. Vox Sang 2011; 101: 154-74.
  10. GANTER MT, Hofer CK. Prinzipien des perioperativen Gerinnungsmanagements. Der Chirurg 2011; 82: 635-43. Gefässchirurgie 2011; 16: 435-44. Der MKG-Chirurg 2012; 5: 77-87. Unfallchirurg 2012; 353-62.
  11. Hofer CK, Rex S, GANTER MT. Update on minimally invasive hemodynamic monitoring in thoracic anesthesia. Curr Opin Anaesthesiol 2014; 27: 28-35.
  12. Steurer MP, GANTER MT. Trauma and massive blood transfusion. Curr Anesthesiol Rep 2014; 4: 200-8.
  13. Steurer MP, GANTER MT. Point-of-care coagulation testing. ASA newsletter 2015; 79(6): 20-2
  14. Thomasin RA, Rich H, GANTER MT. [Wandel der Lehr- und Lernkultur]. VSAO-ASMAC Journal 2015; 5: 10-2.
  15. Steurer MP, GANTER MT. Comparison and contrast of anesthesia practice in Europe and the United States. ASA monitor 2015; 79(12): 18-20

Buchbeiträge

  1. GANTER MT, Hofer CK. Point of care coagulation monitoring: current status of viscoelastic techniques. In: Vincent JL (ed), Yearbook of Intensive Care and Emergency Medicine 2007, Springer-Verlag Berlin Heidelberg New York, pp 834-846, 2007. ISBN 978-3-540-49432-4.
  2. GANTER MT, Pittet JF. Use of paralytics in the ICU. In: Wiener-Kronish JP (ed), Secrets in Critical Care Medicine (fourth revised edition), Hanley and Belfus Inc., Philadelphia, pp 467-73, 2007. ISBN 978-1-416-03206-9. 6
  3. GANTER MT, Pittet JF. Pain management in the ICU. In: Wiener-Kronish JP (ed), Secrets in Critical Care Medicine (4th edition), Hanley and Belfus Inc., Philadelphia, pp 474-80, 2007. ISBN 978-1-416-03206-9.
  4. GANTER MT, Hofer CK. Assessment of the perioperative fluid balance. In: Vincent JL (ed), Yearbook of Intensive Care and Emergency Medicine 2008, Springer-Verlag Berlin Heidelberg New York, pp 523-535, 2008. ISBN 978-3-540-77289-7.
  5. GANTER MT, Hofer CK, Pittet JF. Postoperative intravascular fluid therapy (Chapter 88), Section VII: Postoperative Care. In: Miller RD (ed), Miller’s Anesthesia (7th edition), Churchill Livingstone, Philadelphia PA, pp 2783-803, 2010. ISBN 978-0-443-06959-8.
  6. Baulig W, Spahn DR, GANTER MT. Coagulation, monitoring at the bedside. In: Vincent JL & Hall J (eds), Encyclopedia of Intensive Care Medicine, Springer-Verlag Berlin Heidelberg New York, pp 569-76, 2012. ISBN 978-3-642-00417-9.
  7. GANTER MT, Hofer CK. Grundlagen des Gerinnungsmanagements. In: Eckart J, Forst H, Briegel J (eds), Kompendium und Repetitorium zur interdisziplinären Fort- und Weiterbildung, ecomed MEDIZIN-Verlag Landsberg, 48. Erg.-Lfg. 4/12 pp 1-19, 2012. ISBN 978-3-609-20210-5.
  8. GANTER MT, Hofer CK. Point-of-care coagulation monitoring. In: Ehrenfeld J, Canesson M (eds), Monitoring technologies in acute care environments: a comprehensive guide to patient monitoring technology, In press @ Springer Science+Business Media New York, 329-53, 2014. ISBN 978-1-4614-8556-8.
  9. Hofer CK, Rex S, GANTER MT. Integrative approach for hemodynamic monitoring (Chapter 13). In: Cannesson M, Pearse R (eds), Perioperative hemodynamic monitoring and goal directed therapy: from theory to praxis, Cambridge University Press, pp 107-19, 2014. ISBN 978-1-107-04817-1.

Stand: Dezember 2015