PD Dr. med. Philipp Stein

Originalarbeiten

1. Repression of T-cell function by thionamides is mediated by inhibition of the activator protein-1/nuclear factor of activated T-cells pathway and is associated with a common structure.
   Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Heimrich B, Roesslein M, Schmidt R, Schwer C I, Hoetzel A, Loop T, Pahl H L, Geiger K K, Pannen B H J (2007)
   Mol Pharmacol 72: 1647–1656
   Impact factor: 3.922 (2017)
2. Thionamides inhibit the transcription factor nuclear factor-kappaB by suppression of Rac1 and inhibitor of kappaB kinase alpha.
   Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Roesslein M, Schmidt R, Schwer C I, Loop T, Geiger K K, Pahl H L, Pannen B H J (2008)
   J Pharmacol Exp Ther. 324: 1037–1044, Impact factor: 3.867 (2017)
3. Carbon monoxide inhalation reduces pulmonary inflammatory response during cardiopulmonary bypass in pigs.
   Goebel U, Siepe M, Mecklenburg A, Stein P, Roesslein M, Schwer C I, Schmidt R, Doenst T, Geiger K K, Pahl H L, Schlensak C, Loop T (2008)
   Anesthesiology. 108: 1025–1036, Impact factor: 5.785 (2017)
4. Pulsatile Pulmonary Perfusion During Cardiopulmonary Bypass Reduces the Pulmonary Inflammatory Response.
   Siepe M, Goebel U, Mecklenburg A, Doenst T, Benk C, Stein P, Beyersdorf F, Loop T, Schlensak C (2008).
   Ann Thorac Surg. 86: 115–122, Impact factor: 3.700 (2017)
5. Up-regulation of heme oxygenase-1 by sevoflurane is not dependent on Kupffer cells and associates with ERK1/2 and AP-1 activation in the rat liver.
   Schwer C I, Stoll P, Pietsch U, Stein P, Laqua J, Goebel U, Hoetzel A, Schmidt R (2010)
   Int J Biochem Cell Biol. 42: 1876–1883, Impact factor: 3.505 (2017)
6. Ease and difficulty of pre-hospital airway management in 425 paediatric patients treated by a helicopter emergency medical service: a retrospective analysis.
   Schmidt A R, Ulrich L, Seifert B, Albrecht R, Spahn D R, Stein P (2016)
   Scand J Trauma Resusc Emerg Med. 24: 22, Impact factor: 2.036 (2017)
7. Failure rate of prehospital chest decompression after severe thoracic trauma.
   Kaserer A*, Stein P*, Simmen H P, Spahn D R, Neuhaus V (2017)
   Am J Emerg Med. 35: 469–474, Impact factor: 1.494 (2017)
8. Factors Influencing Quality of Pain Management in a Physician Staffed Helicopter Emergency Medical Service.
   Oberholzer N, Kaserer A, Albrecht R, Seifert B, Tissi M, Spahn D R, Maurer K., Stein P (2017)
   Anesth Analg. 125: 200–209, Impact factor: 4.014 (2017)
9. A smartphone application to determine body length for body weight estimation in children: a prospective clinical trial.
   Wetzel O, Schmidt A R, Seiler M, Scaramuzza D, Seifert B, Spahn D R, Stein P (2017)
   J Clin Monit Comput. 68: 441–451, Impact factor: 2.178 (2017)
10. Impact of city police layperson education and equipment with automatic external defibrillators on patient outcome after out of hospital cardiac arrest.
    Stein P*, Spahn G H*, Müller S, Zollinger A, Baulig W, Brüesch M, Seifert B, Spahn D R (2017)
    Resuscitation. 118: 27–34, Impact factor: 5.230 (2017)
11. Change of transfusion and treatment paradigm in major trauma patients.
    Stein P, Kaserer A, Sprengel K, Wanner G A, Seifert B, Theusinger O M, Spahn D R (2017)
    Anaesthesia. 72: 1317–1326, Impact factor 4.741 (2017)
12. Specialist advice may improve patient selection for decompression therapy following diving accidents: a retrospective observational study.
    Steffensmeier D, Albrecht R, Wendling J, Melliger R, Spahn D R, Stein P, Wyss C (2017)
    Scand J Trauma Resusc Emerg Med. 25: 101, Impact factor: 2.036 (2017)
13. The impact of prehospital tranexamic acid on blood coagulation in trauma patients.
    Stein P*, Studt J D*, Albrecht R, Müller S, von OW D, Fischer S, Seifert B, Mariotti S, Spahn D R, Theusinger O M (2018)
    Anesth Analg. 126: 522–529, Impact factor: 4.014 (2017)
14. Optimisation of the dosage of tranexamic acid in trauma patients with population pharmacokinetic analysis.
    Grassin-Delyle S, Theusinger O M, Albrecht R, Müller S, Spahn D R, Urien S, Stein P (2017)
    Anaesthesia. 73: 719-729, Impact factor: 4.741 (2017)
15. Comparison of two different coagulation algorithms on the use of allogeneic blood products and coagulation factors in severely injured trauma patients.
    Kaserer A, Casutt M, Sprengel K, Seifert B, Spahn D R, Stein P (2018)
    Scand J Trauma Resusc Emerg Med. 26: 4, Impact factor: 2.036 (2018)
16. Risk Factors for Higher-than-Expected Residual Rivaroxaban Plasma Concentrations in Real-Life Patients.
    Kaserer A, Schedler A, Jetter A, Seifert B, Spahn D R, Stein P, Studt J D (2018)
    Thromb Hemost. 118: 808-817, Impact factor: 5.6

Fallberichte

1. Dabigatran anticoagulation and Stanford type A aortic dissection: lethal coincidence: Case report with literature review.
   Stein P, Bosshart M, Brand B, Schlicker A, Spahn D R, Bettex D (2014)
   Acta Anaesthesiol Scand. 58: 630–637, Impact factor: 2.438 (2017)
2. Multiple trauma, resuscitation, and 15 minutes of esophageal intubation: survival without neurologic deficit. 
   Stein P, Albrecht R, Spahn D R (2014)
   Am J Emerg Med. 32: 950.e1–2, Impact factor: 1.494 (2017)
3. Schwieriger präklinischer Atemweg und Bergung an der Rettungswinde.
   Stein P, Meyer J, Mariotti S, Spahn D R, Albrecht R (2015)
   Notarzt. 31: 129–133, Impact factor: 0.318 (2017)
4. Massive coagulopathy caused by the bite of a Crotalus basiliscus snake.
   Meyer S, Hartmann F, Stein P, Lenherr R, Fuchs J, Spahn D R (2017)
   Anaesth Cases. Epub.

Übersichtsarbeiten

1. Applying “Patient Blood Management” in the trauma center.
   Theusinger O M, Stein P, Spahn D R (2014)
   Curr Opin Anaesthesiol. 27: 225–232, Impact factor: IF 2.369 (2017)
2. Transfusion strategy in multiple trauma patients.
   Theusinger O M, Stein P, Spahn D R (2014)
   Curr Opin Crit Care. 20: 646–655, Impact factor: 3.316 (2017)
3. Evidence base for restrictive transfusion triggers in high-risk patients.
   Spahn D R, Spahn G H, Stein P (2015)
   Transfus Med Hemother. 42: 110–114, Impact factor: 1.76 (2017)
4. Point of Care and Factor Concentrate-Based Coagulation Algorithms.
   Theusinger O M, Stein P, Levy J H (2015)
   Transfus Med Hemother. 42: 1–7, Impact factor: 1.76 (2017)
5. Indications and Risks of Fibrinogen in Surgery and Trauma.
   Spahn D R, Spahn G H, Stein P (2015)
   Semin Thromb Hemost. 42: 147–154, Impact factor: 3.629 (2017)
6. Point-of-Care Coagulation Monitoring in Trauma Patients.
   Stein P, Kaserer A, Spahn G H, Spahn D R (2017)
   Semin Thromb Hemost. 43: 367–374, Impact factor: 3.629 (2017)
7. „Patient blood management“ ist heute Standard.
   Spahn D R, Kaserer A, Spahn G H, Stein P (2017)
   Schweiz Med Forum. 17: 1145-1147, Impact factor: 2.068 (2017)
8. Patient Blood Management: Der Standard heute
   Kaserer A, Stein P, Spahn G H, Spahn D R (2017)
   Ther Umsch. 74: 369-376, Impact factor: 0.18 (2017)